Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation

U Fatima, S Roy, S Ahmad, S Ali, WM Elkady… - Frontiers in …, 2022 - frontiersin.org
Bacopa monnieri has been used for centuries in Ayurvedic medicine, alone or in
combination with other herbs, as a memory and learning enhancer, sedative, and anti …

Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies

AS Abdul Manap, S Vijayabalan… - Drug target …, 2019 - journals.sagepub.com
Alzheimer disease is a neurodegenerative disease that is signified by cognitive decline,
memory loss, and erratic behavior. Till date, no cure for Alzheimer exists and the current …

Unveiling the impact of aging on BBB and Alzheimer's disease: Factors and therapeutic implications

VK Nelson, NK Jha, MV Nuli, S Gupta, S Kanna… - Ageing research …, 2024 - Elsevier
Alzheimer's disease (AD) is a highly prevalent neurodegenerative condition that has
devastating effects on individuals, often resulting in dementia. AD is primarily defined by the …

Lycium barbarum Polysaccharides Prevent Memory and Neurogenesis Impairments in Scopolamine-Treated Rats

W Chen, X Cheng, J Chen, X Yi, D Nie, X Sun, J Qin… - PloS one, 2014 - journals.plos.org
Lycium barbarum is used both as a food additive and as a medicinal herb in many countries,
and L. barbarum polysaccharides (LBPs), a major cell component, are reported to have a …

Valine conjugated polymeric nanocarriers for targeted co-delivery of rivastigmine and quercetin in rat model of Alzheimer disease

Z Kaboli, MJ Hosseini, S Sadighian… - International Journal of …, 2023 - Elsevier
Multifunctional nanocarriers are increasingly promising for disease treatment aimed at
finding effective therapy and overcoming barriers in drug delivery. Herein, valine conjugated …

Neuroprotective function of a novel hexapeptide QMDDQ from shrimp via activation of the PKA/CREB/BNDF signaling pathway and its structure–activity relationship

D Wu, S Zhang, N Sun, B Zhu, S Lin - Journal of Agricultural and …, 2020 - ACS Publications
This study aimed to evaluate the neuroprotective function of shrimp-derived peptides
QMDDQ and KMDDQ. Biochemical results revealed that both peptides exhibited …

Botanicals as modulators of neuroplasticity: focus on BDNF

E Sangiovanni, P Brivio, M Dell'Agli… - Neural …, 2017 - Wiley Online Library
The involvement of brain‐derived neurotrophic factor (BDNF) in different central nervous
system (CNS) diseases suggests that this neurotrophin may represent an interesting and …

Born to protect: leveraging BDNF against cognitive deficit in Alzheimer's disease

L Caffino, F Mottarlini, F Fumagalli - CNS drugs, 2020 - Springer
Alzheimer's disease is a chronic neurodegenerative devastating disorder affecting a high
percentage of the population over 65 years of age and causing a relevant emotional, social …

[HTML][HTML] Structure-activity relationship and pathway of antioxidant shrimp peptides in a PC12 cell model

D Wu, M Li, J Ding, J Zheng, BW Zhu, S Lin - Journal of Functional Foods, 2020 - Elsevier
This study aimed to investigate that the antioxidant capacity of the peptides Met-Thr-Thr-Asp-
Ile (MTTNI) and Met-Thr-Thr-Asp-Leu (MTTNL) purified from shrimp protein hydrolysate …

Lactucopicrin ameliorates oxidative stress mediated by scopolamine-induced neurotoxicity through activation of the NRF2 pathway

R Venkatesan, L Subedi, EJ Yeo, SY Kim - Neurochemistry international, 2016 - Elsevier
Cholinergic activity plays a vital role in cognitive function, and is reduced in individuals with
neurodegenerative diseases. Scopolamine, a muscarinic cholinergic antagonist, has been …