The periodontal diseases are highly prevalent and can affect up to 90% of the worldwide
population. Gingivitis, the mildest form of periodontal disease, is caused by the bacterial …

As many diseases have been shown to have several or indirect causes (ie are multifactorial)
the question is what is the relative importance of each factor in a given disease? Also, what …

Aggressive periodontitis is a destructive disease characterized by the following: the
involvement of multiple teeth with a distinctive pattern of periodontal tissue loss; a high rate …

Aim: To review the literature for genetic risk factors associated with periodontitis. Methods:
Computerized search of the literature in English using key words: Periodontitis; Genes; …

In the last 10 years, a rising number of epidemiological investigations have studied the
possible association between chronic oral infections and cardiovascular diseases (CVD) …

Aging is a biological process characterized by time-dependent functional declines that are
influenced by changes in redox status and by oxidative stress-induced inflammatory …

Papillon-Lefèvre syndrome (PLS) results from mutations that inactivate cysteine protease
cathepsin C (CTSC), which processes a variety of serine proteases considered essential for …

Recent advances in human genomics and the advent of molecular medicine have
catapulted our ability to characterize human and health and disease. Scientists and …

Periodontitis is an infectious, inflammatory disease that is associated with a complex
interplay between specific bacteria, host response, and environmental factors. Because of its …

This article critically reviews the evidence for a role of genetic factors in the pathogenesis of
aggressive periodontitis and discusses the study approaches commonly used to identify …