C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

Manganese is found in the active center of numerous enzymes that operate by an outer-
sphere homolytic C–H cleavage. Thus, a plethora of bioinspired radical-based C–H …

In this tutorial review, recent advances in the synthesis of cyclopropane-containing natural
products are discussed, highlighting the application of novel synthetic methodologies and …

Indoline alkaloids constitute a large class of natural products; their diverse and complex
structures contribute to potent biological activities in a range of molecules. Designing an …

Cyclization and annulation reactions initiated by ring-opening of small rings, especially
cyclopropanes and cyclobutanes are now well-established in synthetic chemistry …

This review summarizes synthetic developments reported from 1987 to 2019 that exploit C–
C single bond cleavage of cyclopropylamine-based systems. The synthetic and mechanistic …

We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an
1, 2-amino alcohol in expectation of their synchronous activation of a nucleophile and an …

The importance of chirality is well recognised, mainly in connection with the fact that nearly
all natural products are chiral and their physiological or pharmacological properties depend …

1. INTRODUCTION The catalysis of organic reactions by metals still constitutes one of the
most useful and powerful tools in organic synthesis. 1 Although asymmetric synthesis is …