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Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy
XL Fan, Y Zhang, X Li, QL Fu - Cellular and molecular life sciences, 2020 - Springer
Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …
Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases
Mesenchymal stem cells (MSCs; also referred to as mesenchymal stromal cells) have
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …
Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …
Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine
FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …
their capacity for local engrafting and differentiating into multiple tissue types. However …
Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
The therapeutic potential of mesenchymal stromal cells for regenerative medicine: current knowledge and future understandings
M Merimi, R El-Majzoub, L Lagneaux… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent decades, research on the therapeutic potential of progenitor cells has advanced
considerably. Among progenitor cells, mesenchymal stromal cells (MSCs) have attracted …
considerably. Among progenitor cells, mesenchymal stromal cells (MSCs) have attracted …
Apoptotic vesicles activate autophagy in recipient cells to induce angiogenesis and dental pulp regeneration
Z Li, M Wu, S Liu, X Liu, Y Huan, Q Ye, X Yang, H Guo… - Molecular Therapy, 2022 - cell.com
Extracellular vesicles (EVs) derived from living cells play important roles in donor cell-
induced recipient tissue regeneration. Although numerous studies have found that cells …
induced recipient tissue regeneration. Although numerous studies have found that cells …
Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles
Ischemic stroke is the third cause of death in the developed countries and the main reason
of severe disability. Brain ischemia leads to the production of damage-associated molecular …
of severe disability. Brain ischemia leads to the production of damage-associated molecular …
Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation
D Li, X Liu, W Pi, Y Zhang, L Yu, C Xu, Z Sun… - Frontiers in …, 2022 - frontiersin.org
Doxorubicin (DOX) is an anthracycline antibiotic that is used extensively for the
management of carcinoma; however, its clinical application is limited due to its serious …
management of carcinoma; however, its clinical application is limited due to its serious …
Extracellular membrane vesicles as a mechanism of cell-to-cell communication: advantages and disadvantages
G Turturici, R Tinnirello, G Sconzo… - American Journal of …, 2014 - journals.physiology.org
Microvesicles represent a newly identified mechanism of intercellular communication. Two
different types of microvesicles have been identified: membrane-derived vesicles (EVs) and …
different types of microvesicles have been identified: membrane-derived vesicles (EVs) and …