Pathological calcification of cartilage is a hallmark of osteoarthritis (OA). Calcification can be
observed both at the cartilage surface and in its deeper layers. The formation of calcium …

Osteoarthritis (OA) is a common chronic inflammatory degenerative disease. Since
chondrocytes are the only type of cells in cartilage, their survival is critical for maintaining …

It is recognized that the changes in the physical properties of extracellular matrix (ECM)
result in fine‐tuned cell responses including cell morphology, proliferation and …

Background Arthritis is thought to be closely related to serum uric acid. The study aims to
assess the association between asymptomatic hyperuricemia (AH) and arthritis. Methods A …

Sulfide and transition metals often came together in Biology. The variety of possible
structural combinations enabled living organisms to evolve an array of highly versatile metal …

Ectopic mineralization refers to the deposition of mineralized complexes in the extracellular
matrix of soft tissues. Calcific aortic valve disease, vascular calcification, gallstones, kidney …

Gout is at least three times more prevalent in males than in females. However, concurrent
with rising total gout prevalence, complex factors, including comorbidities, diet, lifestyle, and …

Reactive oxygen species (ROS) metabolism is regulated by the oxygen-mediated enzyme
reaction and antioxidant mechanism within cells under physiological conditions. Xanthine …

Introduction: Accumulation of abnormal crystals in the body, derived from endogenous or
exogenous materials can drive a wide spectrum of inflammatory disease states. It is well …

Aconitum spp. are important medicinal plants mentioned in Ayurveda as Ativisa or
Vatsanabha. The present study aims to evaluate anti‐rheumatic potential in seven Aconitum …