Long noncoding RNAs in cancer metastasis
Metastasis is a major contributor to cancer-associated deaths. It is characterized by a
multistep process that occurs through the acquisition of molecular and phenotypic changes …
multistep process that occurs through the acquisition of molecular and phenotypic changes …
[HTML][HTML] Emerging roles of lncRNA in cancer and therapeutic opportunities
MC Jiang, JJ Ni, WY Cui, BY Wang… - American journal of …, 2019 - ncbi.nlm.nih.gov
Cancer is difficult to cure due to frequent metastasis, and develo** effective therapeutic
approaches to treat cancer is urgently important. Long non-coding RNAs (lncRNAs) have …
approaches to treat cancer is urgently important. Long non-coding RNAs (lncRNAs) have …
Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively …
W Ni, S Yao, Y Zhou, Y Liu, P Huang, A Zhou, J Liu… - Molecular cancer, 2019 - Springer
Background YAP activation is crucial for cancer development including colorectal cancer
(CRC). Nevertheless, it remains unclear whether N6-Methyladenosine (m 6 A) modified …
(CRC). Nevertheless, it remains unclear whether N6-Methyladenosine (m 6 A) modified …
Long noncoding RNA in cancer: wiring signaling circuitry
C Lin, L Yang - Trends in cell biology, 2018 - cell.com
Long noncoding RNAs (lncRNAs), which are encoded by a vast less explored region of the
human genome, may hold missing drivers of cancer and have gained attention recently as a …
human genome, may hold missing drivers of cancer and have gained attention recently as a …
Glucocorticoids promote breast cancer metastasis
MMS Obradović, B Hamelin, N Manevski, JP Couto… - Nature, 2019 - nature.com
Diversity within or between tumours and metastases (known as intra-patient tumour
heterogeneity) that develops during disease progression is a serious hurdle for therapy …
heterogeneity) that develops during disease progression is a serious hurdle for therapy …
Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity
M Katoh - International journal of oncology, 2017 - spandidos-publications.com
Cancer stem cells (CSCs), which have the potential for self-renewal, differentiation and de-
differentiation, undergo epigenetic, epithelial-mesenchymal, immunological and metabolic …
differentiation, undergo epigenetic, epithelial-mesenchymal, immunological and metabolic …
Dynamic transcriptomic m5C and its regulatory role in RNA processing
YS Chen, WL Yang, YL Zhao… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Abstract RNA 5‐methylcytosine (m5C) is a prevalent RNA modification in multiple RNA
species, including messenger RNAs (mRNAs), transfer RNAs (tRNAs), ribosomal RNAs …
species, including messenger RNAs (mRNAs), transfer RNAs (tRNAs), ribosomal RNAs …
The dynamic RNA modification 5‐methylcytosine and its emerging role as an epitranscriptomic mark
L Trixl, A Lusser - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
It is a well‐known fact that RNA is the target of a plethora of modifications which currently
amount to over a hundred. The vast majority of these modifications was observed in the two …
amount to over a hundred. The vast majority of these modifications was observed in the two …
Analysis of the role of the Hippo pathway in cancer
Y Han - Journal of translational medicine, 2019 - Springer
Cancer is a serious health issue in the world due to a large body of cancer-related human
deaths, and there is no current treatment available to efficiently treat the disease as the …
deaths, and there is no current treatment available to efficiently treat the disease as the …
5-methylcytosine RNA methyltransferases and their potential roles in cancer
M Li, Z Tao, Y Zhao, L Li, J Zheng, Z Li… - Journal of translational …, 2022 - Springer
Abstract In recent years, 5-methylcytosine (m5C) RNA modification has emerged as a key
player in regulating RNA metabolism and function through coding as well as non-coding …
player in regulating RNA metabolism and function through coding as well as non-coding …