Acquired and inherited lipodystrophies

A Garg - New England Journal of Medicine, 2004‏ - Mass Medical Soc
Lipodystrophies, heterogeneous acquired or inherited disorders characterized by the
selective loss of adipose tissue, predispose affected patients to insulin resistance and its …

Guidelines for the evaluation and management of dyslipidemia in human immunodeficiency virus (HIV)-infected adults receiving antiretroviral therapy …

MP Dubé, JH Stein, JA Aberg… - Clinical Infectious …, 2003‏ - academic.oup.com
Dyslipidemia is a common problem affecting HIV-infected patients receiving antiretroviral
therapy. Since publication of preliminary guidelines in 2000 [1], numerous studies have …

Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial

JE Gallant, S Staszewski, AL Pozniak, E DeJesus… - Jama, 2004‏ - jamanetwork.com
ContextTenofovir disoproxil fumarate (DF) is a once-daily nucleotide analogue reverse
transcriptase inhibitor. ObjectiveTo evaluate the efficacy and safety of tenofovir DF …

Polylactic acid implants (New-Fill)® to correct facial lipoatrophy in HIV-infected patients: results of the open-label study VEGA

MA Valantin, C Aubron-Olivier, J Ghosn, E Laglenne… - Aids, 2003‏ - journals.lww.com
Background: In the absence of currently available therapy to manage facial lipoatrophy,
strategies used to compensate for facial fat loss warrant clinical evaluation. Methods: The …

An objective case definition of lipodystrophy in HIV-infected adults: a case-control study

A Carr - The Lancet, 2003‏ - thelancet.com
Background Lipodystrophy (peripheral lipoatrophy, central fat accumulation, and
lipomatosis) is a common and disfiguring problem in adult patients with HIV-1 infection on …

Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel

M Schambelan, CA Benson, A Carr… - JAIDS Journal of …, 2002‏ - journals.lww.com
Objective: Alterations in glucose and lipid metabolism, lactic acidemia, bone disorders, and
abnormal body fat distribution have been recognized recently as frequent complications …

No association of abacavir use with myocardial infarction: findings of an FDA meta-analysis

X Ding, E Andraca-Carrera, C Cooper… - JAIDS Journal of …, 2012‏ - journals.lww.com
Background: Several studies have reported an association between abacavir (ABC)
exposure and increased risk of myocardial infarction (MI) among HIV-infected individuals …

Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: the MITOX Extension Study

A Martin, DE Smith, A Carr, C Ringland, J Amin… - Aids, 2004‏ - journals.lww.com
Objective: To determine if long-term improvement in HIV lipoatrophy can be attained by
substitution of thymidine analogues zidovudine (ZDV) or stavudine (d4T) with abacavir …

A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy

GJ Moyle, CA Sabin, J Cartledge, M Johnson, E Wilkins… - Aids, 2006‏ - journals.lww.com
Background: Long-term antiretroviral therapy, while dramatically reducing HIV-related
morbidity and mortality, is associated with metabolic and morphological changes. Peripheral …

Cardiovascular disease in HIV infection

I Sudano, LE Spieker, G Noll, R Corti, R Weber… - American heart …, 2006‏ - Elsevier
The survival of patients with HIV infection who have access to highly active antiretroviral
therapy has dramatically increased. In HIV-infected persons, cardiovascular disease can be …