Neurotransmitters are molecules that amplify, transmit, and convert signals in cells, having
an essential role in information transmission throughout the nervous system. Hundreds of …

Background Glutamate and glutamine are the most abundant amino acids in the blood and
play a crucial role in cell survival in the nervous system. Various transporters found in cell …

Objective Status epilepticus (SE) is a life‐threatening prolonged epileptic seizure that
affects~ 40 per 100 000 people yearly worldwide. The persistence of seizures may lead to …

The human high-affinity sodium–dicarboxylate cotransporter (NaDC3) imports various
substrates into the cell as tricarboxylate acid cycle intermediates, lipid biosynthesis …

In recent years, there has been remarkable progress in the field of dissolution dynamic
nuclear polarization (D-DNP). This method has shown significant potential for enhancing …

Calorie restriction (CR) or a fasting regimen is considered one of the most potent non-
pharmacological interventions to prevent chronic metabolic disorders, ameliorate …

Experiences of discrimination are associated with adverse health outcomes, including
obesity. However, the mechanisms by which discrimination leads to obesity remain unclear …

Background Tuberous sclerosis complex (TSC) and some focal cortical dysplasias (FCDs)
are associated with dysfunctional mTOR signaling, resulting in increased cell growth and …

Human brain development is ongoing throughout childhood, with for example, myelination
of nerve fibers and refinement of synaptic connections continuing until early adulthood. 1H …

Glutamate carboxypeptidase II (GCPII), localized on the surface of astrocytes and activated
microglia, regulates extracellular glutamate concentration in the central nervous system …