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Immune-related adverse events of checkpoint inhibitors
Cancer immunotherapies have changed the landscape of cancer treatment during the past
few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and …
few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and …
Immune-related toxicities of checkpoint inhibitors: mechanisms and mitigation strategies
RJ Sullivan, JS Weber - Nature reviews Drug discovery, 2022 - nature.com
The immune-related adverse events associated with treatment with immune checkpoint
inhibitors result in significant morbidity for patients as well as considerable cost to the health …
inhibitors result in significant morbidity for patients as well as considerable cost to the health …
Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy: ASCO guideline update
PURPOSE To increase awareness, outline strategies, and offer guidance on the
recommended management of immune-related adverse events (irAEs) in patients treated …
recommended management of immune-related adverse events (irAEs) in patients treated …
Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance
Abstract Immune-checkpoint inhibitors (ICIs), including anti-cytotoxic T lymphocyte antigen 4
(CTLA-4), anti-programmed cell death 1 (PD-1) and anti-programmed cell death 1 ligand 1 …
(CTLA-4), anti-programmed cell death 1 (PD-1) and anti-programmed cell death 1 ligand 1 …
Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy: American Society of Clinical Oncology Clinical Practice …
JR Brahmer, C Lacchetti, BJ Schneider… - Journal of Clinical …, 2018 - ascopubs.org
Purpose To increase awareness, outline strategies, and offer guidance on the
recommended management of immune-related adverse events in patients treated with …
recommended management of immune-related adverse events in patients treated with …
Management of immunotherapy-related toxicities, version 1.2019, NCCN clinical practice guidelines in oncology
JA Thompson, BJ Schneider, J Brahmer… - Journal of the National …, 2019 - jnccn.org
The aim of the NCCN Guidelines for Management of Immunotherapy-Related Toxicities is to
provide guidance on the management of immune-related adverse events resulting from …
provide guidance on the management of immune-related adverse events resulting from …
Current diagnosis and management of immune related adverse events (irAEs) induced by immune checkpoint inhibitor therapy
The indications of immune checkpoint inhibitors (ICIs) are set to rise further with the approval
of newer agent like atezolimumab for use in patients with advanced stage urothelial …
of newer agent like atezolimumab for use in patients with advanced stage urothelial …
[HTML][HTML] Neurological adverse events associated with immune checkpoint inhibitors: review of the literature
S Cuzzubbo, F Javeri, M Tissier, A Roumi… - European Journal of …, 2017 - Elsevier
Immune checkpoint inhibitors (ICIs) targeting CTLA4 and PD1 constitute a promising class of
cancer treatment but are associated with several immune-related disorders. We here review …
cancer treatment but are associated with several immune-related disorders. We here review …
Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: analysis of 102 patients
EP Flanagan, SR Hinson, VA Lennon… - Annals of …, 2017 - Wiley Online Library
Objective A novel autoimmune central nervous system (CNS) disorder with glial fibrillary
acidic protein (GFAP)‐IgG as biomarker was recently characterized. Here, 102 patients with …
acidic protein (GFAP)‐IgG as biomarker was recently characterized. Here, 102 patients with …
[HTML][HTML] Late-onset and long-lasting immune-related adverse events from immune checkpoint-inhibitors: an overlooked aspect in immunotherapy
E Ghisoni, A Wicky, H Bouchaab, M Imbimbo… - European Journal of …, 2021 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICIs) have revolutionised cancer
therapy but frequently cause immune-related adverse events (irAEs). Description of late …
therapy but frequently cause immune-related adverse events (irAEs). Description of late …