While Nature harnesses RNA and DNA to store, read and write genetic information, the
inherent programmability, synthetic accessibility and wide functionality of these nucleic acids …

Here we review studies that provided important information about conformational properties
of DNA using circular dichroic (CD) spectroscopy. The conformational properties include the …

Conspectus G-quadruplexes (G4s) are distinctive four-stranded DNA or RNA structures
found within cells that are thought to play functional roles in gene regulation and …

Circular dichroism (CD) is remarkably sensitive to the conformational states of nucleic acids;
therefore, CD spectroscopy has been used to study most features of DNA and RNA …

Guanine-rich DNA sequences can fold into stable four-stranded structures called G-
quadruplexes or G4s. Research in the past decade demonstrated that G4 structures are …

Guanine-rich DNA sequences can form G-quadruplexes stabilized by stacked G–G–G–G
tetrads in monovalent cation-containing solution. The length and number of individual G …

Telomeres play an important role in cellular aging and cancer. Human telomeric DNA and
RNA G‐rich sequences are capable of forming a four‐stranded structure, known as the G …

Formation of the G-quadruplex in the human telomeric sequence can inhibit the activity of
telomerase, thus the intramolecular telomeric G-quadruplexes have been considered as an …

There are many structures that can be adopted by nucleic acids other than the famous
Watson–Crick duplex form. This tutorial review describes the guanine rich G-quadruplex …

Previously, it has been reported that human telomeric DNA sequences could adopt in
different experimental conditions four different intramolecular G-quadruplexes each …