Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

J Ren, NN Wu, S Wang, JR Sowers… - Physiological …, 2021 - journals.physiology.org
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Skeletal muscle: A review of molecular structure and function, in health and disease

K Mukund, S Subramaniam - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

ER stress responses: an emerging modulator for innate immunity

G Di Conza, PC Ho - Cells, 2020 - mdpi.com
The endoplasmic reticulum (ER) is a critical organelle, storing the majority of calcium and
governing protein translation. Thus, it is crucial to keep the homeostasis in all ER …

Abscisic acid as pathogen effector and immune regulator

L Lievens, J Pollier, A Goossens, R Beyaert… - Frontiers in plant …, 2017 - frontiersin.org
Abscisic acid (ABA) is a sesquiterpene signaling molecule produced in all kingdoms of life.
To date, the best known functions of ABA are derived from its role as a major phytohormone …

Enzyme kinetics, molecular docking, and in silico characterization of canary seed (Phalaris canariensis L.) peptides with ACE and pancreatic lipase inhibitory activity

U Urbizo-Reyes, AM Liceaga, L Reddivari… - Journal of Functional …, 2022 - Elsevier
The bioactivity of canary seed peptides (CSP) towards metabolism-regulating enzymes was
evaluated. Peptides with angiotensin-converting enzyme (ACE), dipeptidyl peptidase IV …

Inflammatory and anti‐inflammatory equilibrium, proliferative and antiproliferative balance: the role of cytokines in multiple myeloma

C Musolino, A Allegra, V Innao… - Mediators of …, 2017 - Wiley Online Library
Multiple myeloma (MM) is typically exemplified by a desynchronized cytokine system with
increased levels of inflammatory cytokines. We focused on the contrast between …

[HTML][HTML] Peer reviewed: prevalence of and trends in diabetes among veterans, United States, 2005–2014

Y Liu, S Sayam, X Shao, K Wang, S Zheng… - Preventing chronic …, 2017 - ncbi.nlm.nih.gov
Diabetes is a highly prevalent chronic disease among US adults, and its prevalence among
US veterans is even higher. This study aimed to examine the prevalence of and trends in …

The roles of adipose tissue macrophages in human disease

W Liang, Y Qi, H Yi, C Mao, Q Meng, H Wang… - Frontiers in …, 2022 - frontiersin.org
Macrophages are a population of immune cells functioning in antigen presentation and
inflammatory response. Research has demonstrated that macrophages belong to a cell …

Chromogranin A and its fragments in cardiovascular, immunometabolic, and cancer regulation

SK Mahata, A Corti - Annals of the New York Academy of …, 2019 - Wiley Online Library
Chromogranin A (CgA)—the index member of the chromogranin/secretogranin secretory
protein family—is ubiquitously distributed in endocrine, neuroendocrine, and immune cells …

Macrophage-targeted therapeutics for metabolic disease

KR Peterson, MA Cottam, AJ Kennedy… - Trends in pharmacological …, 2018 - cell.com
Macrophages are cells of the innate immune system that are resident in all tissues, including
metabolic organs such as the liver and adipose tissue (AT). Because of their phenotypic …