Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …
to the rapidly increased prevalence of overweight and obesity. To this point …
Skeletal muscle: A review of molecular structure and function, in health and disease
Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …
the structural and functional complexity of this important anatomical tissue, designed to …
ER stress responses: an emerging modulator for innate immunity
G Di Conza, PC Ho - Cells, 2020 - mdpi.com
The endoplasmic reticulum (ER) is a critical organelle, storing the majority of calcium and
governing protein translation. Thus, it is crucial to keep the homeostasis in all ER …
governing protein translation. Thus, it is crucial to keep the homeostasis in all ER …
Abscisic acid as pathogen effector and immune regulator
Abscisic acid (ABA) is a sesquiterpene signaling molecule produced in all kingdoms of life.
To date, the best known functions of ABA are derived from its role as a major phytohormone …
To date, the best known functions of ABA are derived from its role as a major phytohormone …
Enzyme kinetics, molecular docking, and in silico characterization of canary seed (Phalaris canariensis L.) peptides with ACE and pancreatic lipase inhibitory activity
The bioactivity of canary seed peptides (CSP) towards metabolism-regulating enzymes was
evaluated. Peptides with angiotensin-converting enzyme (ACE), dipeptidyl peptidase IV …
evaluated. Peptides with angiotensin-converting enzyme (ACE), dipeptidyl peptidase IV …
Inflammatory and anti‐inflammatory equilibrium, proliferative and antiproliferative balance: the role of cytokines in multiple myeloma
Multiple myeloma (MM) is typically exemplified by a desynchronized cytokine system with
increased levels of inflammatory cytokines. We focused on the contrast between …
increased levels of inflammatory cytokines. We focused on the contrast between …
[HTML][HTML] Peer reviewed: prevalence of and trends in diabetes among veterans, United States, 2005–2014
Y Liu, S Sayam, X Shao, K Wang, S Zheng… - Preventing chronic …, 2017 - ncbi.nlm.nih.gov
Diabetes is a highly prevalent chronic disease among US adults, and its prevalence among
US veterans is even higher. This study aimed to examine the prevalence of and trends in …
US veterans is even higher. This study aimed to examine the prevalence of and trends in …
The roles of adipose tissue macrophages in human disease
W Liang, Y Qi, H Yi, C Mao, Q Meng, H Wang… - Frontiers in …, 2022 - frontiersin.org
Macrophages are a population of immune cells functioning in antigen presentation and
inflammatory response. Research has demonstrated that macrophages belong to a cell …
inflammatory response. Research has demonstrated that macrophages belong to a cell …
Chromogranin A and its fragments in cardiovascular, immunometabolic, and cancer regulation
Chromogranin A (CgA)—the index member of the chromogranin/secretogranin secretory
protein family—is ubiquitously distributed in endocrine, neuroendocrine, and immune cells …
protein family—is ubiquitously distributed in endocrine, neuroendocrine, and immune cells …
Macrophage-targeted therapeutics for metabolic disease
Macrophages are cells of the innate immune system that are resident in all tissues, including
metabolic organs such as the liver and adipose tissue (AT). Because of their phenotypic …
metabolic organs such as the liver and adipose tissue (AT). Because of their phenotypic …