Post‐transcriptional regulation of messenger RNAs (mRNAs)(ie, mechanisms that control
translation, stability and localization) is a critical focal point in spatiotemporal regulation of …

Messenger RNA (mRNA) stability and translational efficiency are two crucial aspects of the
post-transcriptional process that profoundly impact protein production in a cell. While it is …

Messenger RNA (mRNA) translation by the ribosome represents the final step of a
complicated molecular dance from DNA to protein. Although classically considered a …

The pathogenesis of ischemic diseases remains unclear. Here we demonstrate the
induction of microRNA-668 (miR-668) in ischemic acute kidney injury (AKI) in human …

The rise of systems biology has ushered a new paradigm: the view of the cell as a system
that processes environmental inputs to drive phenotypic outputs. Synthetic biology provides …

A new paradigm has emerged that coding regions can regulate mRNA stability in model
organisms. Here, due to differences in cognate tRNA abundance, synonymous codons are …

Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms
involved are not fully understood. We found that zygotic mRNA stability in Drosophila …

Despite their importance in determining protein abundance, a comprehensive catalogue of
sequence features controlling protein‐to‐mRNA (PTR) ratios and a quantification of their …

Extracellular vesicles with their molecular cargo can modulate target cell response and may
affect the pathogenesis of diseases. The extracellular vesicles containing micro-RNAs …

MicroRNAs (miRNAs) exert a broad influence over gene expression by directing effector
activities that im**e on translation and stability of mRNAs. We recently discovered that the …