Emerging droplet microfluidics

L Shang, Y Cheng, Y Zhao - Chemical reviews, 2017 - ACS Publications
Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …

Single‐cell analysis using droplet microfluidics

K Matuła, F Rivello, WTS Huck - Advanced Biosystems, 2020 - Wiley Online Library
Droplet microfluidics has revolutionized the study of single cells. The ability to
compartmentalize cells within picoliter droplets in microfluidic devices has opened up a wide …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation

DJ Collins, A Neild, A DeMello, AQ Liu, Y Ai - Lab on a Chip, 2015 - pubs.rsc.org
There is a recognized and growing need for rapid and efficient cell assays, where the size of
microfluidic devices lend themselves to the manipulation of cellular populations down to the …

Technologies for single-cell isolation

A Gross, J Schoendube, S Zimmermann… - International journal of …, 2015 - mdpi.com
The handling of single cells is of great importance in applications such as cell line
development or single-cell analysis, eg, for cancer research or for emerging diagnostic …

Inertial microfluidic physics

H Amini, W Lee, D Di Carlo - Lab on a Chip, 2014 - pubs.rsc.org
Microfluidics has experienced massive growth in the past two decades, and especially with
advances in rapid prototy** researchers have explored a multitude of channel structures …

Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery

AS Mao, JW Shin, S Utech, H Wang, O Uzun, W Li… - Nature materials, 2017 - nature.com
Existing techniques to encapsulate cells into microscale hydrogels generally yield high
polymer-to-cell ratios and lack control over the hydrogel's mechanical properties. Here, we …

Inertial focusing in microfluidics

JM Martel, M Toner - Annual review of biomedical engineering, 2014 - annualreviews.org
When Segré and Silberberg in 1961 witnessed particles in a laminar pipe flow congregating
at an annulus in the pipe, scientists were perplexed and spent decades learning why such …

Droplet microfluidics for high-throughput biological assays

MT Guo, A Rotem, JA Heyman, DA Weitz - Lab on a Chip, 2012 - pubs.rsc.org
Droplet microfluidics offers significant advantages for performing high-throughput screens
and sensitive assays. Droplets allow sample volumes to be significantly reduced, leading to …

Droplet based microfluidics

R Seemann, M Brinkmann, T Pfohl… - Reports on progress …, 2011 - iopscience.iop.org
Droplet based microfluidics is a rapidly growing interdisciplinary field of research combining
soft matter physics, biochemistry and microsystems engineering. Its applications range from …