Background The global burden of non-alcoholic fatty liver disease (NAFLD) parallels the
increase in obesity rates across the world. Although overweight and obesity status are …

Objective To identify the optimal dose and modality of exercise for treating major depressive
disorder, compared with psychotherapy, antidepressants, and control conditions. Design …

Objective To evaluate the comparative efficacy and safety of glucagon-like peptide-1
receptor agonists (GLP-1RAs) on glycaemic control, body weight, and lipid profile in adults …

Network meta-analysis compares different interventions for the same condition, by
combining direct and indirect evidence derived from all eligible studies. Network …

Objective To compare the benefits and harms of drug treatments for adults with type 2
diabetes, adding non-steroidal mineralocorticoid receptor antagonists (including finerenone) …

Background Sarcopenia is a serious public health concern among older adults worldwide.
Exercise is the most common intervention for sarcopenia. This study aimed to compare the …

Health economic evaluations are comparative analyses of alternative courses of action in
terms of their costs and consequences. The Consolidated Health Economic Evaluation …

Background Previous meta-analyses have shown reduced risks of composite adverse
events with intravascular imaging-guided percutaneous coronary intervention (PCI) …

Background Mortality rates of coronavirus disease-2019 (COVID-19) continue to rise across
the world. The impact of several risk factors on coronavirus mortality has been previously …

Objective To perform a large-scale pairwise and network meta-analysis on the effects of all
relevant exercise training modes on resting blood pressure to establish optimal …