Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

Nucleic acids are a promising type of therapeutic for the treatment of a wide range of
conditions, including cancer, but they also pose many delivery challenges. For efficient and …

The literature describing the use of low-intensity ultrasound in four major areas of cancer
therapy—sonodynamic therapy, ultrasound-mediated chemotherapy, ultrasound-mediated …

Administration of drugs through oral and intravenous routes is a mainstay of modern
medicine, but this approach suffers from limitations associated with off-target side effects and …

The ability of nanoparticles and macromolecules to passively accumulate in solid tumors
and enhance therapeutic effects in comparison with conventional anticancer agents has …

The regulation of gene expression is a promising therapeutic approach for many intractable
diseases. However, its use in clinical applications requires the efficient delivery of nucleic …

Microbubble ultrasound contrast agents have the potential to dramatically improve gene
therapy treatments by enhancing the delivery of therapeutic DNA to malignant tissue. The …

In recent years, the application of microrobots in precision therapy has gained significant
attention. The small size and maneuverability of these micromachines enable them to …

Microbubbles lower the threshold for cavitation of ultrasound and have multiple potential
therapeutic applications in the cardiovascular system. One of the first therapeutic …