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The proteins of mRNA modification: writers, readers, and erasers
Over the past decade, mRNA modifications have emerged as important regulators of gene
expression control in cells. Fueled in large part by the development of tools for detecting …
expression control in cells. Fueled in large part by the development of tools for detecting …
m6A RNA methylation: from mechanisms to therapeutic potential
RNA carries a diverse array of chemical modifications that play important roles in the
regulation of gene expression. N 6‐methyladenosine (m6A), installed onto mRNA by the …
regulation of gene expression. N 6‐methyladenosine (m6A), installed onto mRNA by the …
RNA demethylation increases the yield and biomass of rice and potato plants in field trials
Abstract RNA N 6-methyladenosine (m6A) modifications are essential in plants. Here, we
show that transgenic expression of the human RNA demethylase FTO in rice caused a more …
show that transgenic expression of the human RNA demethylase FTO in rice caused a more …
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
Abstract N 6-methyladenosine (m6A) is a chemical modification present in multiple RNA
species, being most abundant in mRNAs. Studies on enzymes or factors that catalyze …
species, being most abundant in mRNAs. Studies on enzymes or factors that catalyze …
Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis
Abstract N 6-methyladenosine (m6A) plays critical roles in regulating mRNA metabolism.
However, comprehensive m6A methylomes in different plant tissues with single-base …
However, comprehensive m6A methylomes in different plant tissues with single-base …
The m6A reader ECT8 is an abiotic stress sensor that accelerates mRNA decay in Arabidopsis
Z Cai, Q Tang, P Song, E Tian, J Yang, G Jia - The Plant Cell, 2024 - academic.oup.com
Abstract N 6-methyladenosine (m6A) is the most abundant mRNA modification and plays
diverse roles in eukaryotes, including plants. It regulates various processes, including plant …
diverse roles in eukaryotes, including plants. It regulates various processes, including plant …
Post-transcriptional gene regulation by mRNA modifications
The recent discovery of reversible mRNA methylation has opened a new realm of post-
transcriptional gene regulation in eukaryotes. The identification and functional …
transcriptional gene regulation in eukaryotes. The identification and functional …
A photoregulatory mechanism of the circadian clock in Arabidopsis
Cryptochromes (CRYs) are photoreceptors that mediate light regulation of the circadian
clock in plants and animals. Here we show that CRYs mediate blue-light regulation of N6 …
clock in plants and animals. Here we show that CRYs mediate blue-light regulation of N6 …
N6‐Methyladenosine mRNA methylation is important for salt stress tolerance in Arabidopsis
J Hu, J Cai, SJ Park, K Lee, Y Li, Y Chen… - The Plant …, 2021 - Wiley Online Library
As the most abundant internal modification of mRNA, N6‐methyladenosine (m6A)
methylation of RNA is emerging as a new layer of epitranscriptomic gene regulation in …
methylation of RNA is emerging as a new layer of epitranscriptomic gene regulation in …
m6A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis
P Song, L Wei, Z Chen, Z Cai, Q Lu, C Wang, E Tian… - Genome biology, 2023 - Springer
Background RNA N 6-methyladenosine (m6A) modification is critical for plant growth and
crop yield. m6A reader proteins can recognize m6A modifications to facilitate the functions of …
crop yield. m6A reader proteins can recognize m6A modifications to facilitate the functions of …