[HTML][HTML] Progress on the Anti-Inflammatory Activity and Structure–Efficacy Relationship of Polysaccharides from Medical and Edible Homologous Traditional Chinese …
Y Zhang, X Lin, L **a, S **ong, B **a, J **e, Y Lin, L Lin… - Molecules, 2024 - mdpi.com
Medicinal food varieties developed according to the theory of medical and edible
homologues are effective at preventing and treating chronic diseases and in health care. As …
homologues are effective at preventing and treating chronic diseases and in health care. As …
Targeting mast cells in allergic disease: current therapies and drug repurposing
JR Burchett, JM Dailey, SA Kee, DT Pryor, A Kotha… - Cells, 2022 - mdpi.com
The incidence of allergic disease has grown tremendously in the past three generations.
While current treatments are effective for some, there is considerable unmet need. Mast cells …
While current treatments are effective for some, there is considerable unmet need. Mast cells …
Molecular mechanisms of obesity predisposes to atopic dermatitis
D Shang, S Zhao - Frontiers in Immunology, 2024 - frontiersin.org
Obesity is a prevalent metabolic disease that reduces bacterial diversity, colonizes the
epidermis with lipophilic bacteria, and increases intestinal pro-inflammatory species, all of …
epidermis with lipophilic bacteria, and increases intestinal pro-inflammatory species, all of …
Acinar cells and the development of pancreatic fibrosis
J An, T Jiang, L Qi, K **e - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Pancreatic fibrosis is caused by excessive deposition of extracellular matrixes of collagen
and fibronectin in the pancreatic tissue as a result of repeated injury often seen in patients …
and fibronectin in the pancreatic tissue as a result of repeated injury often seen in patients …
Application of In Vitro Models for Studying the Mechanisms Underlying the Obesogenic Action of Endocrine-Disrupting Chemicals (EDCs) as Food Contaminants—A …
M Kowalczyk, JP Piwowarski, A Wardaszka… - International Journal of …, 2023 - mdpi.com
Obesogenic endocrine-disrupting chemicals (EDCs) belong to the group of environmental
contaminants, which can adversely affect human health. A growing body of evidence …
contaminants, which can adversely affect human health. A growing body of evidence …
Inflammatory signaling pathways in the treatment of Alzheimer's disease with inhibitors, natural products and metabolites
Y Zheng, X Zhang, R Zhang… - International …, 2023 - spandidos-publications.com
The intricate nature of Alzheimer's disease (AD) pathogenesis poses a persistent obstacle to
drug development. In recent times, neuroinflammation has emerged as a crucial pathogenic …
drug development. In recent times, neuroinflammation has emerged as a crucial pathogenic …
Is the peroxisome proliferator-activated receptor gamma a putative target for epilepsy treatment? Current evidence and future perspectives
The peroxisome proliferator-activated receptor gamma (PPARγ), which belongs to the family
of nuclear receptors, has been mainly studied as an important factor in metabolic disorders …
of nuclear receptors, has been mainly studied as an important factor in metabolic disorders …
PPARs in Clinical Experimental Medicine after 35 Years of Worldwide Scientific Investigations and Medical Experiments
A Skoczyńska, M Ołdakowska, A Dobosz, R Adamiec… - Biomolecules, 2024 - mdpi.com
This year marks the 35th anniversary of Professor Walter Wahli's discovery of the PPARs
(Peroxisome Proliferator-Activated Receptors) family of nuclear hormone receptors. To mark …
(Peroxisome Proliferator-Activated Receptors) family of nuclear hormone receptors. To mark …
Structural biology inspired development of a series of human peroxisome proliferator-activated receptor gamma (PPARγ) ligands: From agonist to antagonist
H Miyachi - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent progress in the structural and molecular pharmacological understanding of the
nuclear receptor, peroxisome proliferator-activated receptor gamma (hPPARγ)—a …
nuclear receptor, peroxisome proliferator-activated receptor gamma (hPPARγ)—a …
MicroRNA Let-7 Induces M2 macrophage polarization in COPD emphysema through the IL-6/STAT3 pathway
T Liu, Z Zhang, W Shen, Y Wu… - International Journal of …, 2023 - Taylor & Francis
Background M2 polarized macrophages are involved in the occurrence and development of
emphysema in COPD patients. However, the molecular mechanism of M2 macrophage …
emphysema in COPD patients. However, the molecular mechanism of M2 macrophage …