Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention
One quarter of the global population is estimated to have nonalcoholic fatty liver disease
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …
Gut-liver axis: Pathophysiological concepts and clinical implications
H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
C Depommier, A Everard, C Druart, H Plovier… - Nature medicine, 2019 - nature.com
Metabolic syndrome is characterized by a constellation of comorbidities that predispose
individuals to an increased risk of develo** cardiovascular pathologies as well as type 2 …
individuals to an increased risk of develo** cardiovascular pathologies as well as type 2 …
The gut-liver axis in liver disease: Pathophysiological basis for therapy
The gut-liver axis refers to the bidirectional relationship between the gut and its microbiota,
and the liver, resulting from the integration of signals generated by dietary, genetic and …
and the liver, resulting from the integration of signals generated by dietary, genetic and …
From NASH to HCC: current concepts and future challenges
Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …
Gut microbiota and immune system interactions
Dynamic interactions between gut microbiota and a host's innate and adaptive immune
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …
The gut microbiota and host health: a new clinical frontier
Over the last 10–15 years, our understanding of the composition and functions of the human
gut microbiota has increased exponentially. To a large extent, this has been due to new …
gut microbiota has increased exponentially. To a large extent, this has been due to new …
Dietary lipids, gut microbiota and lipid metabolism
M Schoeler, R Caesar - Reviews in endocrine and metabolic disorders, 2019 - Springer
The gut microbiota is a central regulator of host metabolism. The composition and function of
the gut microbiota is dynamic and affected by diet properties such as the amount and …
the gut microbiota is dynamic and affected by diet properties such as the amount and …
The gut–liver axis and the intersection with the microbiome
In the past decade, an exciting realization has been that diverse liver diseases—ranging
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …