Myelin-oligodendrocyte glycoprotein antibody-associated disease

R Marignier, Y Hacohen, A Cobo-Calvo… - The Lancet …, 2021‏ - thelancet.com
Myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently
identified autoimmune disorder that presents in both adults and children as CNS …

Reaching an evidence-based prognosis for personalized treatment of multiple sclerosis

D Rotstein, X Montalban - Nature Reviews Neurology, 2019‏ - nature.com
Personalized treatment is ideal for multiple sclerosis (MS) owing to the heterogeneity of
clinical features, but current knowledge gaps, including validation of biomarkers and …

Evolving concepts in the treatment of relapsing multiple sclerosis

G Comi, M Radaelli, PS Sørensen - The Lancet, 2017‏ - thelancet.com
In the past 20 years the treatment scenario of multiple sclerosis has radically changed. The
increasing availability of effective disease-modifying therapies has shifted the aim of …

Progressive multiple sclerosis: prospects for disease therapy, repair, and restoration of function

D Ontaneda, AJ Thompson, RJ Fox, JA Cohen - The Lancet, 2017‏ - thelancet.com
Multiple sclerosis is a major cause of neurological disability, which accrues predominantly
during progressive forms of the disease. Although development of multifocal inflammatory …

Digital biomarkers in multiple sclerosis

A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021‏ - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …

Outcome measures in clinical trials for multiple sclerosis

CEP van Munster, BMJ Uitdehaag - CNS drugs, 2017‏ - Springer
Due to the heterogeneous nature of the disease, it is a challenge to capture disease activity
of multiple sclerosis (MS) in a reliable and valid way. Therefore, it can be difficult to assess …

Optical coherence tomography in multiple sclerosis: a 3‐year prospective multicenter study

F Paul, PA Calabresi, F Barkhof… - Annals of clinical …, 2021‏ - Wiley Online Library
Objective To evaluate changes over 3 years in the thickness of inner retinal layers including
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …

Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021‏ - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Optical coherence tomography angiography: technical principles and clinical applications in ophthalmology

AM Hagag, SS Gao, Y Jia, D Huang - Taiwan journal of …, 2017‏ - journals.lww.com
Optical coherence tomography angiography (OCTA) is a functional extension of OCT that
provides information on retinal and choroidal circulations without the need for dye injections …

Optical coherence tomography in multiple sclerosis

J Britze, JL Frederiksen - Eye, 2018‏ - nature.com
To summarize recent findings regarding the utility of optical coherence tomography in
multiple sclerosis. We searched PubMed for relevant articles using the keywords 'optical …