Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …

We report the progress on an electron-activated dissociation (EAD) device coupled to a
quadrupole TOF mass spectrometer (QqTOF MS) developed in our group. This device …

In-depth structural characterization of lipids is an essential component of lipidomics. There
has been a rapid expansion of mass spectrometry methods that are capable of resolving …

The chemical complexity of biological tissues creates challenges in the analysis of lipids via
imaging mass spectrometry. The presence of isobaric and isomeric compounds introduces …

Mass spectrometry imaging (MSI) enables the spatial distributions of molecules possessing
different mass‐to‐charge ratios to be mapped within complex environments revealing …

Mass spectrometry imaging (MSI) of lipids within tissues has significant potential for both
biomolecular discovery and histopathological applications. Conventional MSI technologies …

Accurate structural identification of lipids in imaging mass spectrometry is critical to properly
contextualizing spatial distributions with tissue biochemistry. Gas-phase charge inversion …

Over the past decade, mass spectrometry (MS)-based “shotgun lipidomics” has emerged as
a powerful tool for quantitative and qualitative analysis of the complex lipids in the biological …

The biological functions of lipids largely depend on their chemical structures. The position
and configuration of C= C bonds are two of the essential attributes that determine the …