DNA as a target for antimicrobials

A Bolhuis, JR Aldrich-Wright - Bioorganic chemistry, 2014 - Elsevier
Resistance to antimicrobials is one of the biggest threats to our healthcare. However, in the
last few decades very few truly novel antimicrobial compounds have been brought to market …

Recent uses of Kröhnke methodology: a short survey

I Sasaki - Synthesis, 2016 - thieme-connect.com
The scope of this short review is to point out how such an old reaction as the Kröhnke-type
ring closure is still used nowadays to enable simple access to pyridines or polypyridines …

Fluorescence and absorption studies of DNA–Pd (II) complex interaction: Synthesis, spectroanalytical investigations and biological activities

KP Thakor, MV Lunagariya, BS Bhatt… - Luminescence, 2019 - Wiley Online Library
Abstract Novel palladium (II) complexes (7a–7e) of substituted quinoline derivatives were
synthesized. The complexes were characterized using various techniques such as …

A novel water-soluble Cu (II) gluconate complex inhibits cancer cell growth by triggering apoptosis and ferroptosis related mechanisms

DH Cai, BF Liang, BH Chen, QY Liu, ZY Pan… - Journal of Inorganic …, 2023 - Elsevier
Metal copper complexes have attracted extensive attention as potential alternatives to
platinum-based anticancer drugs due to their possible different modes of action. Herein, a …

Visible light-driven photocatalysts, quantum chemical calculations, ADMET-SAR parameters, and DNA binding studies of nickel complex of sulfadiazine

SB Pandya, BN Socha, RP Dubey, UH Patel… - Scientific Reports, 2023 - nature.com
A 3D-supramolecular nickel integrated Ni-SDZ complex was synthesized using sodium salt
of sulfadiazine as the ligand and nickel (II) acetate as the metal salt using a condensation …

[HTML][HTML] Synthesis, characterization, biomolecular interaction, cytotoxicity, and computational studies of quinoxaline-based platinum (II) complexes

MP Dhaduk, RA Dabhi, VD Bhatt, BS Bhatt… - Results in Chemistry, 2024 - Elsevier
The combination of ninhydrin and o-phenylenediamine, followed by their reaction with a
phenylhydrazine derivative produces quinoxaline-based ligands (L 1–L 6). These ligands …

Nickel doped bismuth sulfide nanomaterials: Synthesis, characterization, and enhancement of anti-microbial activity

V Darji, P Desai, MP Deshpande, S Chaki… - Materials Chemistry and …, 2023 - Elsevier
This study aims to evaluate the minimum inhibitory concentration (MIC) of pristine Bi 2 S 3
and Ni-doped Bi 2 S 3 nanostructures for their anti-microbial study. The nanostructures were …

Direct CH/CLi coupling of 1, 2, 4-triazines with C6F5Li followed by aza-Diels-Alder reaction as a pot, atom, and step economy (PASE) approach towards novel …

TD Moseev, MV Varaksin, DA Gorlov… - Journal of Fluorine …, 2019 - Elsevier
An original pot, atom, and step economy (PASE) approach towards novel pentafluorophenyl-
substituted 2, 2′-bipyridine fluorophores, as well as their triazine precursors via oxidative …

Cell apoptosis induced by ciprofloxacin based Cu (II) complexes: cytotoxicity, SOD mimic and antibacterial studies

BS Bhatt, DH Gandhi, FU Vaidya… - Journal of …, 2021 - Taylor & Francis
The current cancer research focuses on the design and synthesis of chemical compounds
that can modulate cell apoptosis or programmed cell death. So we synthesized and …