OBJECTIVES: This study aimed to conduct a comprehensive and updated systematic review
with network meta-analysis (NMA) to assess the outcome benefits of various blood …

Background Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to a
significant social burden. East Asian herbal medicine (EAHM) has long been used to treat …

Background The comparative safety and efficacy of the biologics currently approved for
asthma are unclear. Objective We compared the safety and efficacy of mepolizumab …

To maintain current cognitive function and access greater cognitive reserves,
nonpharmacological interventions may be a viable alternative for older adults with or without …

Background Intranasal agents may be ideal for the treatment of migraine patients. Many new
acute intranasal-specific therapies have been developed, but few of them have been directly …

Purpose We aimed to provide clinicians with introductory guidance for interpreting and
assessing confidence in on Network meta-analysis (NMA) results. Methods We reviewed …

Introduction: Sorafenib was historically the standard of care for advanced hepatocellular
carcinoma (aHCC) until it was superseded by the combination of atezolizumab and …

Background Direct-acting oral anticoagulants (DOACs) have demonstrated superior efficacy
in preventing stroke and death compared with warfarin in patients with atrial fibrillation (AF) …

Network meta-analysis is a powerful tool to synthesize evidence from independent studies
and compare multiple treatments simultaneously. A critical task of performing a network …

Background While memantine has been considered a promising drug for migraine
prevention, no conclusive evidence exists comparing its efficacy with other migraine …