Arcuate nucleus-dependent regulation of metabolism—pathways to obesity and diabetes mellitus
A Jais, JC Brüning - Endocrine reviews, 2022 - academic.oup.com
The central nervous system (CNS) receives information from afferent neurons, circulating
hormones, and absorbed nutrients and integrates this information to orchestrate the actions …
hormones, and absorbed nutrients and integrates this information to orchestrate the actions …
Freezing revisited: coordinated autonomic and central optimization of threat co**
Animals have sophisticated mechanisms for co** with danger. Freezing is a unique state
that, upon threat detection, allows evidence to be gathered, response possibilities to be …
that, upon threat detection, allows evidence to be gathered, response possibilities to be …
A comprehensive overview on stress neurobiology: basic concepts and clinical implications
Stress is recognized as an important issue in basic and clinical neuroscience research,
based upon the founding historical studies by Walter Canon and Hans Selye in the past …
based upon the founding historical studies by Walter Canon and Hans Selye in the past …
Considering sex as a biological variable in basic and clinical studies: an endocrine society scientific statement
Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …
Neurobiology of fear and specific phobias
R Garcia - Learning & memory, 2017 - learnmem.cshlp.org
Fear, which can be expressed innately or after conditioning, is triggered when a danger or a
stimulus predicting immediate danger is perceived. Its role is to prepare the body to face this …
stimulus predicting immediate danger is perceived. Its role is to prepare the body to face this …
Central nervous system control of gastrointestinal motility and secretion and modulation of gastrointestinal functions
KN Browning, RA Travagli - Comprehensive physiology, 2014 - pmc.ncbi.nlm.nih.gov
Although the gastrointestinal (GI) tract possesses intrinsic neural plexuses that allow a
significant degree of autonomy over GI functions, the central nervous system (CNS) provides …
significant degree of autonomy over GI functions, the central nervous system (CNS) provides …
Neural mechanisms of social homeostasis
GA Matthews, KM Tye - Annals of the New York Academy of …, 2019 - Wiley Online Library
Social connections are vital to survival throughout the animal kingdom and are dynamic
across the life span. There are debilitating consequences of social isolation and loneliness …
across the life span. There are debilitating consequences of social isolation and loneliness …
Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states
Lateral hypothalamus (LH) neurons containing the neuropeptide hypocretin (HCRT; orexin)
modulate affective components of arousal, but their relevant synaptic inputs remain poorly …
modulate affective components of arousal, but their relevant synaptic inputs remain poorly …
Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity
K Timper, JC Brüning - Disease models & mechanisms, 2017 - journals.biologists.com
The 'obesity epidemic'represents a major global socioeconomic burden that urgently calls
for a better understanding of the underlying causes of increased weight gain and its …
for a better understanding of the underlying causes of increased weight gain and its …
Reciprocal control of obesity and anxiety–depressive disorder via a GABA and serotonin neural circuit
The high comorbidity between obesity and mental disorders, such as depression and
anxiety, often exacerbates metabolic and neurological symptoms significantly. However …
anxiety, often exacerbates metabolic and neurological symptoms significantly. However …