It is widely accepted that regular physical activity is beneficial for cardiovascular health.
Frequent exercise is robustly associated with a decrease in cardiovascular mortality as well …

Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …

Cardiac fibroblasts convert to myofibroblasts with injury to mediate healing after acute
myocardial infarction (MI) and to mediate long-standing fibrosis with chronic disease …

Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …

Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …

The heart has a high rate of ATP production and turnover that is required to maintain its
continuous mechanical work. Perturbations in ATP-generating processes may therefore …

Chronic kidney disease (CKD) is a worldwide public health threat that increases risk of
death due to cardiovascular complications, including left ventricular hypertrophy (LVH) …

Cardiovascular disease is the leading cause of death in patients with chronic kidney disease
(CKD). As CKD progresses, CKD-specific risk factors, such as disordered mineral …

Patients with chronic kidney disease (CKD) develop increased levels of the phosphate-
regulating hormone, fibroblast growth factor (FGF) 23, that are associated with a higher risk …

The heart hypertrophies in response to developmental signals as well as increased
workload. Although adult-onset hypertrophy can ultimately lead to disease, cardiac …