Context Although polycystic ovary syndrome (PCOS) is the most common endocrinopathy
affecting women of reproductive age, risk factors that may cause the syndrome are poorly …

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer, and it is
currently the third most common cause of cancer death in the USA Progress in the fight …

Consistent with the concept of the gut-brain phenomenon, observational studies suggest a
relationship between Alzheimer's disease (AD) and gastrointestinal tract (GIT) disorders; …

For any given level of overall adiposity, individuals vary considerably in fat distribution. The
inherited basis of fat distribution in the general population is not fully understood. Here, we …

Background Type 2 diabetes mellitus (T2DM) is a chronic, metabolic disorder in which
concomitant insulin resistance and β-cell impairment lead to hyperglycemia, influenced by …

OBJECTIVE Fat content and volume of liver and pancreas are associated with risk of
diabetes in observational studies; whether these associations are causal is unknown. We …

Background: Some individuals living with obesity may be relatively metabolically healthy,
whilst others suffer from multiple conditions that may be linked to adverse metabolic effects …

Maternal education was strongly correlated with adolescent brain morphology, cognitive
performances, and mental health. However, the molecular basis for the effects of maternal …

Background This study aims to comprehensively investigate the phenotypic and genetic
relationships between four common lipids (high-density lipoprotein cholesterol, HDL-C; low …

A growing body of evidence suggests that intrapancreatic fat is associated with diabetes, but
whether distribution of intrapancreatic fat across the regions of the pancreas has a …