The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The
characteristic of RA is gradual joint deterioration. Current RA treatment alleviates signs such …

The purpose of this research was to formulate, optimize, and characterize ambrisentan
chitosan-coated LeciPlex (AMS-CTS-LPX) to increase the therapeutic effectiveness and …

Diabetes mellitus is a life-threatening metabolic disease. At the moment, there is no effective
treatment available to combat it. In this study, we aimed to develop berberine-loaded …

In the present study, we aimed to formulate, optimize, and characterize azithromycin
chitosan coated niosomes (AZM-CTS-NSM) as a novel colloidal system that increases …

Numerous neurological disorders have a pathophysiology that involves an increase in free
radical production in the brain. Quercetin (QER) is a nutraceutical compound that shields the …

While the advent of nano-engineered drug delivery systems (DDSs) has revived hopes for
better management of a wide range of pathologies, critical appraisal of the field has shown …

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects 1% of the
world's population. It is a progressive condition that causes joint inflammation, polyarticular …

This work aimed to develop and produce lacosamide-loaded niosomes coated with chitosan
(LCA-CTS-NSM) using a thin-film hydration method and the Box-Behnken design. The effect …