Hydrogels are polymeric networks with tridimensional structure, which are able to load water
and other substances. Such property makes hydrogels suitable for innumerous applications …

Background: Antibiotics are considered the backbone of rosacea management, especially
for controlling inflammatory papules and pustules. We aim to evaluate the efficacy and safety …

Tacrolimus is a macrolide immunosuppressant widely used in organ transplantation. Due to
the narrow treatment window, therapeutic drug monitoring of the clinical application of …

We have developed a composite hydrogel for improved topical delivery of the poorly soluble
drug Tacrolimus (TAC) to psoriasis lesions. TAC is efficiently solubilized in methoxy poly …

Background Topical application of tacrolimus (FK506) was effective in the treatment of atopic
dermatitis (AD); however, adverse effects frequently occurred with the increase of FK506 …

Objective The objective of this study was to evaluate the efficacy and safety of topical low-
dose tacrolimus (0.01%) solution in patients with vernal keratoconjunctivitis (VKC). Patients …

Epidermolysis bullosa (EB) is a rare genetic dermatosis characterized by skin fragility and
blister formation. With a wide phenotypic spectrum and potential extracutaneous …

Background No long-term maintenance therapy has been tested in patients with seborrheic
dermatitis (SD). Objective We sought to compare the efficacy and tolerance of tacrolimus …

Tacrolimus (TRL) is used for the treatment of atopic dermatitis (AD) due to its T-cell
stimulation effect. However, its significantly poor water solubility, low penetration and …

Atopic dermatitis (AD) remains a challenging condition, with conventional treatments often
leading to adverse effects and limited efficacy. This review explores the diverse landscape of …