Plant pan-genomes are the new reference

PE Bayer, AA Golicz, A Scheben, J Batley, D Edwards - Nature plants, 2020 - nature.com
Recent years have seen a surge in plant genome sequencing projects and the comparison
of multiple related individuals. The high degree of genomic variation observed led to the …

Plant NLR diversity: the known unknowns of pan-NLRomes

AC Barragan, D Weigel - The Plant Cell, 2021 - academic.oup.com
Plants and pathogens constantly adapt to each other. As a consequence, many members of
the plant immune system, and especially the intracellular nucleotide-binding site leucine …

[HTML][HTML] Pan-genome of wild and cultivated soybeans

Y Liu, H Du, P Li, Y Shen, H Peng, S Liu, GA Zhou… - Cell, 2020 - cell.com
Soybean is one of the most important vegetable oil and protein feed crops. To capture the
entire genomic diversity, it is needed to construct a complete high-quality pan-genome from …

Graph-based pan-genome reveals structural and sequence variations related to agronomic traits and domestication in cucumber

H Li, S Wang, S Chai, Z Yang, Q Zhang, H **n… - Nature …, 2022 - nature.com
Structural variants (SVs) represent a major source of genetic diversity and are related to
numerous agronomic traits and evolutionary events; however, their comprehensive …

Pangenomics comes of age: from bacteria to plant and animal applications

AA Golicz, PE Bayer, PL Bhalla, J Batley, D Edwards - Trends in Genetics, 2020 - cell.com
The pangenome refers to a collection of genomic sequence found in the entire species or
population rather than in a single individual; the sequence can be core, present in all …

Extensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structure

SP Gordon, B Contreras-Moreira, DP Woods… - Nature …, 2017 - nature.com
While prokaryotic pan-genomes have been shown to contain many more genes than any
individual organism, the prevalence and functional significance of differentially present …

Homoeologous exchange is a major cause of gene presence/absence variation in the amphidiploid Brassica napus

B Hurgobin, AA Golicz, PE Bayer… - Plant biotechnology …, 2018 - Wiley Online Library
Homoeologous exchanges (HE s) have been shown to generate novel gene combinations
and phenotypes in a range of polyploid species. Gene presence/absence variation (PAV) is …

Plant pan-genomics comes of age

L Lei, E Goltsman, D Goodstein, GA Wu… - Annual Review of …, 2021 - annualreviews.org
A pan-genome is the nonredundant collection of genes and/or DNA sequences in a species.
Numerous studies have shown that plant pan-genomes are typically much larger than the …

DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites

M Krolevets, V Cate, JH Prochaska, A Schulz… - Clinical …, 2023 - Springer
Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …

Metabolomics and complementary techniques to investigate the plant phytochemical cosmos

H Tsugawa, A Rai, K Saito, R Nakabayashi - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Plants and their associated microbial communities are known to
produce millions of metabolites, a majority of which are still not characterized and are …