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Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
Escherichia coli in Europe: An Overview
Escherichia coli remains one of the most frequent causes of several common bacterial
infections in humans and animals. E. coli is the prominent cause of enteritis, urinary tract …
infections in humans and animals. E. coli is the prominent cause of enteritis, urinary tract …
Antimicrobial peptides towards clinical application—A long history to be concluded
L Cresti, G Cappello, A Pini - International Journal of Molecular Sciences, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are molecules with an amphipathic structure that enables
them to interact with bacterial membranes. This interaction can lead to membrane crossing …
them to interact with bacterial membranes. This interaction can lead to membrane crossing …
Antimicrobial peptides: an overview of a promising class of therapeutics
A Giuliani, G Pirri, S Nicoletto - Open Life Sciences, 2007 - degruyter.com
Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …
[HTML][HTML] Alpha-helical antimicrobial peptides—Using a sequence template to guide structure–activity relationship studies
I Zelezetsky, A Tossi - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2006 - Elsevier
An important class of cytolytic antimicrobial peptides (AMPs) assumes an amphipathic, α-
helical conformation that permits efficient interaction with biological membranes. Host …
helical conformation that permits efficient interaction with biological membranes. Host …
Recent developments in antimicrobial-peptide-conjugated gold nanoparticles
U Rajchakit, V Saro**i - Bioconjugate chemistry, 2017 - ACS Publications
The escalation of multidrug-resistant pathogens has created a dire need to develop novel
ways of addressing this global therapeutic challenge. Because of their antimicrobial …
ways of addressing this global therapeutic challenge. Because of their antimicrobial …
Nanoparticulate antibiotic systems as antibacterial agents and antibiotic delivery platforms to fight infections
Today's human society, product of decades of progress in all fields of knowledge, would
have been unimaginable without the discovery of antibiotics and more generally of …
have been unimaginable without the discovery of antibiotics and more generally of …
Designer peptide and protein dendrimers: a cross-sectional analysis
Dendrimers have attracted immense interest in science and technology due to their unique
chemical structure that offers a myriad of opportunities for researchers. Dendritic design …
chemical structure that offers a myriad of opportunities for researchers. Dendritic design …
Challenges and future prospects of antibiotic therapy: from peptides to phages utilization
Bacterial infections are raising serious concern across the globe. The effectiveness of
conventional antibiotics is decreasing due to global emergence of multi-drug-resistant …
conventional antibiotics is decreasing due to global emergence of multi-drug-resistant …
[HTML][HTML] Natural antimicrobial peptides as inspiration for design of a new generation antifungal compounds
M Bondaryk, M Staniszewska, P Zielińska… - Journal of fungi, 2017 - mdpi.com
Invasive fungal infections are associated with high mortality rates, despite appropriate
antifungal therapy. Limited therapeutic options, resistance development and the high …
antifungal therapy. Limited therapeutic options, resistance development and the high …