Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges

M Nemati, B Singh, RA Mir, M Nemati, A Babaei… - Cell Communication and …, 2022 - Springer
Background Many eukaryote cells produce membrane-enclosed extracellular vesicles (EVs)
to establish cell-to-cell communication. Plant-derived EVs (P-EVs) contain proteins, RNAs …

Technology insight: Plant-derived vesicles—How far from the clinical biotherapeutics and therapeutic drug carriers?

M Cong, S Tan, S Li, L Gao, L Huang, HG Zhang… - Advanced drug delivery …, 2022 - Elsevier
Within the past decades, extracellular vesicles (EVs) have emerged as important mediators
of intercellular communication in both prokaryotes and higher eukaryotes to regulate a …

Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy

C Liu, X Yan, Y Zhang, M Yang, Y Ma, Y Zhang… - Journal of …, 2022 - Springer
Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by
diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current …

[HTML][HTML] Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment

Q Yi, Z Xu, A Thakur, K Zhang, Q Liang, Y Liu… - Pharmacological …, 2023 - Elsevier
Natural compounds are widely used to prevent and treat various diseases due to their
antioxidant and anti-inflammatory effects. As a kind of promising natural compound, plant …

New insights into gut-bacteria-derived indole and its derivatives in intestinal and liver diseases

X Li, B Zhang, Y Hu, Y Zhao - Frontiers in Pharmacology, 2021 - frontiersin.org
The interaction between host and microorganism widely affects the immune and metabolic
status. Indole and its derivatives are metabolites produced by the metabolism of tryptophan …

The emerging role of plant-derived exosomes-like nanoparticles in immune regulation and periodontitis treatment

Z Zhang, Y Yu, G Zhu, L Zeng, S Xu, H Cheng… - Frontiers in …, 2022 - frontiersin.org
Periodontitis is an infectious oral disease, which leads to the destruction of periodontal
tissues and tooth loss. Although the treatment of periodontitis has improved recently, the …

Extracellular vesicles as a novel mediator of interkingdom communication

J Huang, X Wang, Z Wang, L Deng, Y Wang… - Cytokine & Growth …, 2023 - Elsevier
Extracellular vesicles (EVs) are nanosized lipid bilayer-delimited particles secreted from
almost all types of cells including bacteria, mammals and plants, and are presumed to be …

[HTML][HTML] Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis

K Sundaram, J Mu, A Kumar, J Behera, C Lei… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Obesity is becoming a global epidemic and reversing the pathological
processes underlying obesity and metabolic co-morbidities is challenging. Obesity induced …

Plant‐derived exosome‐like nanoparticles: A concise review on its extraction methods, content, bioactivities, and potential as functional food ingredient

S Suharta, A Barlian, AC Hidajah… - Journal of food …, 2021 - Wiley Online Library
Plant‐derived exosome‐like nanoparticles (PDENs) are small vesicles released by
multivesicular bodies mainly to communicate between cells and regulate immunity against …

Extracellular vesicles from plants: current knowledge and open questions

O Urzì, S Raimondo, R Alessandro - International Journal of Molecular …, 2021 - mdpi.com
The scientific interest in the beneficial properties of natural substances has been recognized
for decades, as well as the growing attention in extracellular vesicles (EVs) released by …