The outer membranes of Gram-negative bacteria, mitochondria, and chloroplasts all contain
transmembrane β-barrel proteins. These β-barrel proteins serve essential functions in cargo …

Outer membrane vesicles (OMVs) are spherical, bilayered, and nanosized membrane
vesicles that are secreted from gram-negative bacteria. OMVs play a pivotal role in …

Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading
innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial …

Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

Presently, most simulations of ion channel function rely upon nonatomistic Brownian
dynamics calculations, indirect interpretation of energy maps, or application of external …

Aggregation of the amyloid-forming α-synuclein (αS) protein is closely associated with the
etiology of Parkinson's disease (PD), the most common motor neurodegenerative disorder …

Alzheimer's disease and Parkinson's disease are neurodegenerative disorders
characterised by the misfolding of proteins into soluble prefibrillar aggregates. These …

Mitochondria control various processes that are integral to cellular and organismal
homeostasis, including Ca 2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not …

The bacterial pathogen Neisseria gonorrhoeae is able to invade epithelial cells and survive
intracellularly. During this process, it secretes outer membrane vesicles (OMVs), however …

The modulation of host cell death pathways by bacteria has been recognized as a major
pathogenicity mechanism. Among other strategies, bacterial pathogens can hijack the cell …