Supercritical fluid extraction: Recent advances and applications

M Herrero, JA Mendiola, A Cifuentes… - Journal of Chromatography …, 2010 - Elsevier
Among the different extraction techniques used at analytical and preparative scale,
supercritical fluid extraction (SFE) is one of the most used. This review covers the most …

Supercritical fluid technology: a promising approach in pharmaceutical research

P Girotra, SK Singh, K Nagpal - Pharmaceutical development and …, 2013 - Taylor & Francis
Supercritical fluids possess the unique properties of behaving like liquids and gases, above
their critical point. Supercritical fluid technology has recently emerged as a green and novel …

Optical resolution methods

E Fogassy, M Nógrádi, D Kozma, G Egri… - Organic & …, 2006 - pubs.rsc.org
Despite the large number of elaborate enantioselective syntheses for the preparation of a
single enantiomer to achieve industrial and scientific goals, the separation and purification …

Processing pharmaceutical compounds using dense gas technology

N Foster, R Mammucari, F Dehghani… - Industrial & …, 2003 - ACS Publications
Dense gas techniques, which utilize the properties of fluids in the vicinity of the critical point,
are increasingly being used for the processing of pharmaceuticals. Dense gases are unique …

Enantioselective ring-closing C–H amination of urea derivatives

Z Zhou, Y Tan, T Yamahira, S Ivlev, X **e, R Riedel… - Chem, 2020 - cell.com
An enantioselective intramolecular C (sp 3)–H amination of N-benzoyloxyurea by using a
chiral-at-metal ruthenium catalyst is reported, providing chiral 2-imidazolidinones in yields of …

Chiral separation of underivatized amino acids by reactive extraction with palladium− BINAP complexes

BJV Verkuijl, AJ Minnaard, JG de Vries… - The Journal of organic …, 2009 - ACS Publications
In answer to the need for a more economic technology for the separation of racemates, a
novel system for reactive enantioselective liquid− liquid extraction (ELLE) is introduced …

Separation processes for organic molecules using SCF Technologies

LS Daintree, A Kordikowski, P York - Advanced drug delivery reviews, 2008 - Elsevier
Supercritical fluids have been applied for many years for the separation of solutes from
solids or solute mixtures in both exploratory and industrial applications. In the …

Asymmetric synthesis using hydrolytic enzymes in supercritical carbon dioxide

T Matsuda, T Harada, K Nakamura, T Ikariya - Tetrahedron: Asymmetry, 2005 - Elsevier
Asymmetric synthesis using hydrolytic enzymes in supercritical carbon dioxide -
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Chiral separation of substituted phenylalanine analogues using chiral palladium phosphine complexes with enantioselective liquid–liquid extraction

BJV Verkuijl, B Schuur, AJ Minnaard… - Organic & …, 2010 - pubs.rsc.org
Chiral palladium phosphine complexes have been employed in the chiral separation of
amino acids and phenylalanine analogues in particular. The use of (S)-xylyl-BINAP as a …

Enantioselective liquid–liquid extraction of (R, S)-phenylglycinol using a bisnaphthyl phosphoric acid derivative as chiral extractant

B Schuur, BJV Verkuijl, J Bokhove, AJ Minnaard… - Tetrahedron, 2011 - Elsevier
This study demonstrates that enantioseparation by liquid–liquid extraction can be done in a
continuous flow mode on both laboratory and industrial scale and is a promising technique …