Obesity and asthma
S Miethe, A Karsonova, A Karaulov, H Renz - Journal of Allergy and …, 2020 - Elsevier
Obesity has been well recognized as an important comorbidity in patients with asthma,
representing a unique phenotype and endotype. This association indicates a close …
representing a unique phenotype and endotype. This association indicates a close …
Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems
F Palm, ML Onozato, Z Luo… - American Journal of …, 2007 - journals.physiology.org
Asymmetric (NG, NG)-dimethylarginine (ADMA) inhibits nitric oxide (NO) synthases (NOS).
ADMA is a risk factor for endothelial dysfunction, cardiovascular mortality, and progression …
ADMA is a risk factor for endothelial dysfunction, cardiovascular mortality, and progression …
Asymmetric dimethylarginine (ADMA) as an important risk factor for the increased cardiovascular diseases and heart failure in chronic kidney disease
X Liu, X Xu, R Shang, Y Chen - Nitric oxide, 2018 - Elsevier
Patients with chronic kidney disease have an increased cardiovascular morbidity and
mortality. It has been recognized that the traditional cardiovascular risk factors could only …
mortality. It has been recognized that the traditional cardiovascular risk factors could only …
Immunobiology of nitric oxide and regulation of inducible nitric oxide synthase
M Lee, K Rey, K Besler, C Wang, J Choy - Macrophages: Origin, Functions …, 2017 - Springer
Nitric oxide (NO) is a bioactive gas that has multiple roles in innate and adaptive immune
responses. In macrophages, nitric oxide is produced by inducible nitric oxide synthase upon …
responses. In macrophages, nitric oxide is produced by inducible nitric oxide synthase upon …
Emerging molecular phenotypes of asthma
Although asthma has long been considered a heterogeneous disease, attempts to define
subgroups of asthma have been limited. In recent years, both clinical and statistical …
subgroups of asthma have been limited. In recent years, both clinical and statistical …
[HTML][HTML] Regulation of inducible nitric oxide synthase (iNOS) and its potential role in insulin resistance, diabetes and heart failure
Nitric oxide synthases (NOS) are the enzymes responsible for nitric oxide (NO) generation.
NO is a reactive oxygen species as well as a reactive nitrogen species. It is a free radical …
NO is a reactive oxygen species as well as a reactive nitrogen species. It is a free radical …
Oxidative stress in airway diseases
F Holguin - Annals of the American Thoracic Society, 2013 - atsjournals.org
Airway oxidative stress is broadly defined as an imbalance between prooxidative and
antioxidative processes in the airway. Given its direct exposure to the environment, the lung …
antioxidative processes in the airway. Given its direct exposure to the environment, the lung …
Asthma and obesity: mechanisms and clinical implications
Obesity is the most common asthma co-morbidity; it has been associated with increased risk
for asthma exacerbations, worse respiratory symptoms and poor control. The exact …
for asthma exacerbations, worse respiratory symptoms and poor control. The exact …
An Association between l-Arginine/Asymmetric Dimethyl Arginine Balance, Obesity, and the Age of Asthma Onset Phenotype
Rationale: Increasing body mass index (BMI) has been associated with less fractional
exhaled nitric oxide (FeNO). This may be explained by an increase in the concentration of …
exhaled nitric oxide (FeNO). This may be explained by an increase in the concentration of …
Importance of oxidative stress in the pathogenesis and treatment of asthma
MA Riedl, AE Nel - Current opinion in allergy and clinical …, 2008 - journals.lww.com
Our current understanding of the role of oxidative stress in asthma suggests that antioxidant
therapy may be important in optimizing asthma treatment and prevention. The future success …
therapy may be important in optimizing asthma treatment and prevention. The future success …