Maintenance of lipid asymmetry across the two leaflets of the plasma membrane (PM)
bilayer is a ubiquitous feature of eukaryotic cells. Loss of this asymmetry has been widely …

Cellulose is the most abundant biological compound on Earth and while it is the
predominant building constituent of plants, it is also a key extracellular matrix component in …

Biological membranes consist of two leaflets of phospholipid molecules that form a bilayer,
each leaflet comprising a distinct lipid composition. This asymmetry is created and …

Gram-negative bacteria build an asymmetric outer membrane (OM), with
lipopolysaccharides (LPS) and phospholipids (PLs) occupying the outer and inner leaflets …

Integral membrane proteins are localized and/or regulated by lipids present in the
surrounding bilayer. While bacteria have relatively simple membranes, there is ample …

The synthesis of ATP, life's “universal energy currency,” is the most prevalent chemical
reaction in biological systems and is responsible for fueling nearly all cellular processes …

Pentameric ligand-gated ion channels (pLGICs) mediate synaptic transmission and are
sensitive to their lipid environment. The mechanism of phospholipid modulation of any …

The spatial and temporal coordination of protein transport is an essential cornerstone of the
bacterial adaptation to different environmental conditions. By adjusting the protein …

Bacterial infections in humans and animals caused by multidrug-resistant (MDR) pathogens
pose a serious threat to public health. New antibacterial targets are extremely urgent to …

The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …