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Role of oxidative stress in ocular diseases: a balancing act
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …
NADPH oxidase in brain injury and neurodegenerative disorders
Oxidative stress is a common denominator in the pathology of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral …
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral …
[HTML][HTML] Fabrication of thermal insulation geopolymer bricks using ferrosilicon slag and alumina waste
The present study introduces the preparation of thermal insulation geopolymer bricks using
ferrosilicon slag and alumina waste. Compressive strength, bulk density, cold and boiling …
ferrosilicon slag and alumina waste. Compressive strength, bulk density, cold and boiling …
Evolution of NADPH oxidase inhibitors: selectivity and mechanisms for target engagement
S Altenhöfer, KA Radermacher… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress, an excess of reactive oxygen species (ROS) production
versus consumption, may be involved in the pathogenesis of different diseases. The only …
versus consumption, may be involved in the pathogenesis of different diseases. The only …
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and
collateral formation, stroke, and heart failure. In this review, we discuss in detail the …
collateral formation, stroke, and heart failure. In this review, we discuss in detail the …
A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes
Chronic renal and vascular oxidative stress in association with an enhanced inflammatory
burden are determinant processes in the development and progression of diabetic …
burden are determinant processes in the development and progression of diabetic …
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease
S Altenhöfer, PWM Kleikers, KA Radermacher… - Cellular and Molecular …, 2012 - Springer
Reactive oxygen species (ROS) are cellular signals but also disease triggers; their relative
excess (oxidative stress) or shortage (reductive stress) compared to reducing equivalents …
excess (oxidative stress) or shortage (reductive stress) compared to reducing equivalents …
The phagocyte respiratory burst: Historical perspectives and recent advances
DC Thomas - Immunology letters, 2017 - Elsevier
When exposed to certain stimuli, phagocytes (including neutrophils, macrophages and
eosinophils) undergo marked changes in the way they handle oxygen. Firstly, their rate of …
eosinophils) undergo marked changes in the way they handle oxygen. Firstly, their rate of …
NADPH oxidases: a perspective on reactive oxygen species production in tumor biology
JL Meitzler, S Antony, Y Wu, A Juhasz… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Reactive oxygen species (ROS) promote genomic instability, altered signal
transduction, and an environment that can sustain tumor formation and growth. The NOX …
transduction, and an environment that can sustain tumor formation and growth. The NOX …
NADPH oxidase in the vasculature: Expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension
GA Knock - Free Radical Biology and Medicine, 2019 - Elsevier
The last 20–25 years have seen an explosion of interest in the role of NADPH oxidase
(NOX) in cardiovascular function and disease. In vascular smooth muscle and endothelium …
(NOX) in cardiovascular function and disease. In vascular smooth muscle and endothelium …