Role of oxidative stress in ocular diseases: a balancing act

DY Shu, S Chaudhary, KS Cho, A Lennikov, WP Miller… - Metabolites, 2023 - mdpi.com
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

NADPH oxidase in brain injury and neurodegenerative disorders

MW Ma, J Wang, Q Zhang, R Wang… - Molecular …, 2017 - Springer
Oxidative stress is a common denominator in the pathology of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral …

[HTML][HTML] Fabrication of thermal insulation geopolymer bricks using ferrosilicon slag and alumina waste

MM Ahmed, KAM El-Naggar, D Tarek, A Ragab… - Case Studies in …, 2021 - Elsevier
The present study introduces the preparation of thermal insulation geopolymer bricks using
ferrosilicon slag and alumina waste. Compressive strength, bulk density, cold and boiling …

Evolution of NADPH oxidase inhibitors: selectivity and mechanisms for target engagement

S Altenhöfer, KA Radermacher… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress, an excess of reactive oxygen species (ROS) production
versus consumption, may be involved in the pathogenesis of different diseases. The only …

Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system

B Lassègue, A San Martín, KK Griendling - Circulation research, 2012 - ahajournals.org
atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and
collateral formation, stroke, and heart failure. In this review, we discuss in detail the …

A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes

JC Jha, F Ho, C Dan, K Jandeleit-Dahm - Clinical Science, 2018 - portlandpress.com
Chronic renal and vascular oxidative stress in association with an enhanced inflammatory
burden are determinant processes in the development and progression of diabetic …

The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

S Altenhöfer, PWM Kleikers, KA Radermacher… - Cellular and Molecular …, 2012 - Springer
Reactive oxygen species (ROS) are cellular signals but also disease triggers; their relative
excess (oxidative stress) or shortage (reductive stress) compared to reducing equivalents …

The phagocyte respiratory burst: Historical perspectives and recent advances

DC Thomas - Immunology letters, 2017 - Elsevier
When exposed to certain stimuli, phagocytes (including neutrophils, macrophages and
eosinophils) undergo marked changes in the way they handle oxygen. Firstly, their rate of …

NADPH oxidases: a perspective on reactive oxygen species production in tumor biology

JL Meitzler, S Antony, Y Wu, A Juhasz… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Reactive oxygen species (ROS) promote genomic instability, altered signal
transduction, and an environment that can sustain tumor formation and growth. The NOX …

NADPH oxidase in the vasculature: Expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension

GA Knock - Free Radical Biology and Medicine, 2019 - Elsevier
The last 20–25 years have seen an explosion of interest in the role of NADPH oxidase
(NOX) in cardiovascular function and disease. In vascular smooth muscle and endothelium …