Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …

Novel targets to arrest neurodegeneration in several dementing conditions involving
misfolded protein accumulations may be found in the diverse signaling pathways of the …

Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

Branched-chain amino acids (BCAAs) are critical for skeletal muscle and whole-body
anabolism and energy homeostasis. They also serve as signaling molecules, for example …

Exercise is an effective strategy for diabetes management but is limited by the phenomenon
of exercise resistance (ie, the lack of or the adverse response to exercise on metabolic …

Metabolic syndrome (MetS) is intricately linked to dysregulation of gut microbiota and host
metabolomes. Here, we first find that a purified citrus polymethoxyflavone-rich extract …

Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …

Metabolic syndrome (MetS) consists of several medical conditions that collectively predict
the risk for cardiovascular disease better than the sum of individual conditions. The risk of …