Intervertebral disc (IVD) degeneration is a major cause of low back pain, a prevalent and
chronic condition that has a striking effect on quality of life. Currently, no approved …

Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …

Background. Degenerative disc disease may cause severe low-back pain, a large public
health problem with significant economic and life quality impact. Chronic cases often require …

Background Degenerative disc disease often causes severe low-back pain, a public health
problem with huge economic and life quality impact. Chronic cases often require surgery …

Background The stem cell-based therapies for intervertebral disc degeneration have been
widely studied. However, the mechanisms of mesenchymal stem cells interacting with …

Recent studies have shown that mesenchymal stem cell (MSC)‐based therapy might be an
effective approach for the treatment of intervertebral disc degeneration (IDD). However …

Previous studies showed that coculture of primary chondrocytes (PCs) with various sources
of multipotent cells results in a higher relative amount of cartilage matrix formation than …

Intervertebral disc degeneration (IDD) is a common disease that increases with age, and its
occurrence is stressful both psychologically and financially. Stem cell therapy for IDD is …

In this study, we aimed at investigating the interactions between primary chondrocytes and
mesenchymal stem/stromal cells (MSC) accounting for improved chondrogenesis in …

Earlier, we have shown that the increased cartilage production in pellet co-cultures of
chondrocytes and bone marrow-derived mesenchymal stem cells (BM-MSCs) is due to a …