Zwitterionic biomaterials

Q Li, C Wen, J Yang, X Zhou, Y Zhu, J Zheng… - Chemical …, 2022 - ACS Publications
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

Stealth nanoparticles in oncology: Facing the PEG dilemma

S Zalba, TLM Ten Hagen, C Burgui… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …

Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization

G Sanità, B Carrese, A Lamberti - Frontiers in molecular biosciences, 2020 - frontiersin.org
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …

Surface modifications of nanoparticles for stability in biological fluids

L Guerrini, RA Alvarez-Puebla, N Pazos-Perez - Materials, 2018 - mdpi.com
Due to the high surface: volume ratio and the extraordinary properties arising from the
nanoscale (optical, electric, magnetic, etc.), nanoparticles (NPs) are excellent candidates for …

Energy transfer with semiconductor quantum dot bioconjugates: a versatile platform for biosensing, energy harvesting, and other develo** applications

N Hildebrandt, CM Spillmann, WR Algar, T Pons… - Chemical …, 2017 - ACS Publications
Luminescent semiconductor quantum dots (QDs) are one of the more popular nanomaterials
currently utilized within biological applications. However, what is not widely appreciated is …

An overview of nanoparticles commonly used in fluorescent bioimaging

OS Wolfbeis - Chemical Society Reviews, 2015 - pubs.rsc.org
This article gives an overview of the various kinds of nanoparticles (NPs) that are widely
used for purposes of fluorescent imaging, mainly of cells and tissues. Following an …

Surface functionalization of nanoparticles with polyethylene glycol: effects on protein adsorption and cellular uptake

B Pelaz, P del Pino, P Maffre, R Hartmann, M Gallego… - ACS …, 2015 - ACS Publications
Here we have investigated the effect of enshrouding polymer-coated nanoparticles (NPs)
with polyethylene glycol (PEG) on the adsorption of proteins and uptake by cultured cells …

Toward biocompatible semiconductor quantum dots: from biosynthesis and bioconjugation to biomedical application

J Zhou, Y Yang, C Zhang - Chemical reviews, 2015 - ACS Publications
The understanding of biological systems at the molecular scale is increasingly reliant on the
capability of tracking miscellaneous biomolecules and their events with improved spatial …

Influence of surface chemistry and morphology of nanoparticles on protein corona formation

R Bilardo, F Traldi, A Vdovchenko… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nanomaterials offer promising solutions as drug delivery systems and imaging agents in
response to the demand for better therapeutics and diagnostics. However, the limited …

Zwitteration: coating surfaces with zwitterionic functionality to reduce nonspecific adsorption

JB Schlenoff - Langmuir, 2014 - ACS Publications
Coating surfaces with thin or thick films of zwitterionic material is an effective way to reduce
or eliminate nonspecific adsorption to the solid/liquid interface. This review tracks the …