The ability of the brain to store and process information relies on changing the strength of
connections between neurons. Synaptic facilitation is a form of short-term plasticity that …

Most neuronal communication relies upon the synchronous release of neurotransmitters,
which occurs through synaptic vesicle exocytosis triggered by action potential invasion of a …

Different types of synapses are specialized to interpret spike trains in their own way by virtue
of the complement of short-term synaptic plasticity mechanisms they possess. Numerous …

The physical distance between presynaptic Ca2+ channels and the Ca2+ sensors that
trigger exocytosis of neurotransmitter-containing vesicles is a key determinant of the …

We survey recent analytical approaches to studying the spatiotemporal dynamics of
continuum neural fields. Neural fields model the large-scale dynamics of spatially structured …

Abstract Calcium (Ca2+) signaling is essential for regulating dopamine (DA) concentration
levels in neurons. The alterations in the different mechanisms of [Ca2+] dynamics can cause …

The classical mechanistic idea of nature that prevailed in science during the eighteenth and
nineteenth centuries was an essentially mindless conception: the physically described …

Annexins are a family of structurally related proteins that exhibit Ca2+-dependent binding to
phospholipids. They have been described in many organisms from mammals to molds and …

Calcium signaling underlies much of physiology. Almost all the Ca2+ in the cytoplasm is
bound to buffers, with typically only∼ 1% being freely ionized at resting levels in most cells …

IN synapses, a rise in presynaptic intracellular calcium leads to secretory vesicle fusion in
less than a millisecond, as indicated by the short delay from excitation to postsynaptic …