Genetic parts and enabling tools for biocircuit design

F Buson, Y Gao, B Wang - ACS Synthetic Biology, 2024 - ACS Publications
Synthetic biology aims to engineer biological systems for customized tasks through the
bottom-up assembly of fundamental building blocks, which requires high-quality libraries of …

Engineering genetic circuits: advancements in genetic design automation tools and standards for synthetic biology

L Buecherl, CJ Myers - Current opinion in microbiology, 2022 - Elsevier
Highlights•Synthetic biology aims to apply engineering principles in biology.•Insufficient part
libraries, standards, and software are challenges to the field.•Working on the challenges will …

A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against post-consumer plastics

G Di Rocco, HN Taunt, M Berto, HO Jackson… - Scientific Reports, 2023 - nature.com
Polyethylene terephthalate hydrolases (PETases) are a newly discovered and industrially
important class of enzymes that catalyze the enzymatic degradation of polyethylene …

Micro/Nano Circuits and Systems Design and Design Automation: Challenges and Opportunities [Point of View]

G Cauwenberghs, J Cong, XS Hu, S Joshi… - Proceedings of the …, 2023 - ieeexplore.ieee.org
The field of design and design automation of micro-/nano-circuits and systems has played a
pivotal role in advancing information technologies that are an inseparable part of all our …

Ensemble detection of DNA engineering signatures

A Adler, JS Bader, B Basnight, BW Booth… - ACS Synthetic …, 2024 - ACS Publications
Synthetic biology is creating genetically engineered organisms at an increasing rate for
many potentially valuable applications, but this potential comes with the risk of misuse or …

[HTML][HTML] Computing within bacteria: Programming of bacterial behavior by means of a plasmid encoding a perceptron neural network

AG Becerra, M Gutiérrez, R Lahoz-Beltra - Biosystems, 2022 - Elsevier
In nature, bacteria exhibit a limited repertoire of behaviors in response to environmental
changes. Synthetic biology has now opened up the possibility of programming cells or …

Synbiosuite: a tool for improving the workflow for genetic design and modeling

Z Sents, TE Stoughton, L Buecherl… - ACS Synthetic …, 2023 - ACS Publications
Synthetic biology research has led to the development of many software tools for designing,
constructing, editing, simulating, and sharing genetic parts and circuits. Among these tools …

[HTML][HTML] Bioinformational trends in grape and wine biotechnology

TA Dixon, TC Williams, IS Pretorius - Trends in Biotechnology, 2022 - cell.com
The creative destruction caused by the coronavirus pandemic is yielding immense
opportunity for collaborative innovation networks. The confluence of biosciences …

Building an open representation for biological protocols

B Bartley, J Beal, M Rogers, D Bryce… - ACM Journal on …, 2023 - dl.acm.org
Laboratory protocols are critical to biological research and development, yet difficult to
communicate and reproduce across projects, investigators, and organizations. While many …

Toward FAIR representations of microbial interactions

AR Pacheco, C Pauvert, D Kishore, D Segrè - MSystems, 2022 - journals.asm.org
Despite an ever-growing number of data sets that catalog and characterize interactions
between microbes in different environments and conditions, many of these data are neither …