Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although
recent advances in cell-based models, including human-induced pluripotent stem cell …

Despite the significant decline in mortality, cardiovascular diseases are still the leading
cause of death worldwide. Among them, myocardial infarction (MI) seems to be the most …

Computational techniques have significantly advanced our understanding of cardiac
electrophysiology, yet they have predominantly concentrated on averaged models that do …

Characterizing patient-specific atrial conduction properties is important for understanding
arrhythmia drivers, for predicting potential arrhythmia pathways, and for personalising …

Aims Maladaptive ventricular remodeling is a major cause of ventricular arrhythmias
following myocardial infarction (MI) and adversely impacts the quality of life of affected …

Optical map** is a powerful imaging technique widely adopted to measure membrane
potential changes and intracellular Ca2+ variations in excitable tissues using voltage …

Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …

The fungicide Tebuconazole is a widely used pesticide in agriculture and may cause
cardiotoxicity. In our present investigation the effect of Tebuconazole on the sodium current …

Transmural action potential duration differences and transmural conduction gradients aid
the synchronization of left ventricular repolarization, reducing vulnerability to transmural …

Background Cardiac optical map** is an imaging technique that measures fluorescent
signals across a cardiac preparation. Dual optical imaging of voltage-sensitive and calcium …