Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

We present a review of neuroimaging studies of normal adult aging conducted with diffusion
tensor imaging (DTI) and data from one of the first longitudinal studies using DTI to study …

There has been much recent interest in using magnetic resonance diffusion imaging to
provide information about anatomical connectivity in the brain, by measuring the anisotropic …

The integrity of white matter, as measured in vivo with diffusion tensor imaging (DTI), is
disrupted in normal aging. A current consensus is that in adults advancing age affects …

Normal aging is accompanied by decline in selective cognitive and motor functions. A
concurrent decline in regional white matter integrity, detectable with diffusion tensor imaging …

BACKGROUND: Excessive alcohol use can cause macrostructural tissue shrinkage with
regional preference for frontal systems. The extent and locus of alcoholism's effect on white …

The corpus callosum, the principal white matter structure enabling interhemispheric
information transfer, is heterogeneous in its microstructural composition, heterotopic in its …

A substantial proportion of individuals infected with human immunodeficiency virus (HIV)
also abuse alcohol. Given that each condition can disrupt brain structural integrity, with a …

BACKGROUND AND PURPOSE: The early postnatal period is perhaps the most dynamic
phase of white matter development. We hypothesized that the early postnatal development …

This paper provides a review of MRI and diffusion tensor imaging (DTI) findings in normal
ageing as an essential context for evaluating imaging in dementia, and adding to the ever …