Brief research on the biophysical study and anticancer behavior of Pt (II) complexes: their DNA/BSA binding, molecular docking, and cytotoxic property
The potent bidentate carrier ligand 2-picolylamine (pic) has been used to synthesize Pt (II)
complexes to know their bioactivity and anticancer property as reflected by PASS prediction …
complexes to know their bioactivity and anticancer property as reflected by PASS prediction …
Photodynamic Effect of Amphiphilic N∧C∧N-Coordinated Platinum(II) Complexes in Human Umbilical Vein Endothelial Cells
S Hattori, M Ogishima, T Nakajima, S Hosoya… - Inorganic …, 2024 - ACS Publications
Here, we report a photodynamic therapy (PDT) photosensitizer of N∧ C∧ N-coordinated Pt
(II) complexes:[Pt (L)(solv)]+(HL= 1, 3-(2-dipyridyl) benzene) and [Pt (L)]+@ HSA, which is …
(II) complexes:[Pt (L)(solv)]+(HL= 1, 3-(2-dipyridyl) benzene) and [Pt (L)]+@ HSA, which is …
Anticancer activity and biomolecular interaction of Pt (II) complexes: Their synthesis, characterisation and DFT study
Abstract Cis‐[Pt (TEEDA) Cl2]; 1 (where TEEDA= N, N, N′‐triethylethylenediamine) was
synthesised, and its SCXRD structure was determined. Complex 1 crystallises in the …
synthesised, and its SCXRD structure was determined. Complex 1 crystallises in the …
Design, synthesis, pharmacological evaluation and DNA interaction studies of binuclear Pt (II) complexes with pyrazolo [1, 5‐a] pyrimidine scaffold
MV Lunagariya, KP Thakor, BN Waghela… - Applied …, 2018 - Wiley Online Library
Substituted pyrazolo [1, 5‐a] pyrimidine ligands were synthesized by cyclization, using 3‐
(thiophen‐2‐yl)‐1H‐pyrazol‐5‐amine with substituted enones (3‐phenyl‐1‐(pyridin‐2‐yl) …
(thiophen‐2‐yl)‐1H‐pyrazol‐5‐amine with substituted enones (3‐phenyl‐1‐(pyridin‐2‐yl) …
A Transparent and Injectable Biomaterial Prepared by Mixing Collagen and Anti‐Cancer Platinum Derivatives
SF Ichise, T Koide - Macromolecular Bioscience, 2024 - Wiley Online Library
This study presents the synthesis of a cross‐linked collagen material, named platinum‐
containing collagen gel (PCG), which is achieved by simply mixing collagen and derivatives …
containing collagen gel (PCG), which is achieved by simply mixing collagen and derivatives …
In vitro model reaction of sulfur containing bio-relevant ligands with Pt (ii) complex: Kinetics, mechanism, bioactivity and computational studies
cis-[Pt (MAMP) Cl2] 1 and its hydrolysed product cis-[Pt (MAMP)(H2O) 2] 2+ 2 (where
MAMP= 2-[(N-methylamino) methyl] pyridine) were synthesised and characterised by …
MAMP= 2-[(N-methylamino) methyl] pyridine) were synthesised and characterised by …
PdII–PdII bonding interaction in dinuclear PdII complex with non-macrocyclic (O&N) chelates: Characterization, kinetics and DFT study
A unique Pd II complex with metal–metal (d 8–d 8) bonding interaction,[Pd (pic)(cbdca)] 2· H
2 O 4 (where, pic= 2-aminomethylpyridine and cbdca 2−= cyclobutane-1, 1-dicarboxylate) …
2 O 4 (where, pic= 2-aminomethylpyridine and cbdca 2−= cyclobutane-1, 1-dicarboxylate) …
An experimental and theoretical approach on the kinetics and mechanism for the formation of a four-membered (S, S) chelated Pt (II) complex
The interaction of a chemoprotective agent, diethyldithiocarbamate (DDTC), with cis-[Pt
(pic)(H2O) 2] 2+, 2 (where pic= 2-aminomethylpyridine), in aqueous medium was …
(pic)(H2O) 2] 2+, 2 (where pic= 2-aminomethylpyridine), in aqueous medium was …
Interaction of bio-relevant thio-ether and thiols with dinuclear Pd (II) complex: kinetics, mechanism, bioactivity in aqueous medium and molecular docking
The kinetics of interaction between [Pd (pic)(OH)] 2 (ClO4) 2, 2 (pic= 2-aminomethylpyridine)
with the selected ligands (L) DL-methionine (DL-meth), L-cysteine (L-cys) and N-acetyl-L …
with the selected ligands (L) DL-methionine (DL-meth), L-cysteine (L-cys) and N-acetyl-L …
Kinetic and mechanistic study of substitution on a cytotoxic PtII complex with biologically relevant thiols and a density functional study
I Mitra, S Mukherjee, SC Moi - Polyhedron, 2017 - Elsevier
A systematic investigation of the interactions of platinum antitumor complexes with sulfur-
containing biomolecules is of paramount importance to gain an insight into platinum …
containing biomolecules is of paramount importance to gain an insight into platinum …