miRNA targets: from prediction tools to experimental validation
G Riolo, S Cantara, C Marzocchi, C Ricci - Methods and protocols, 2020 - mdpi.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in both animals
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
Emerging biosensing approaches for microRNA analysis
RM Graybill, RC Bailey - Analytical chemistry, 2016 - ACS Publications
Background and Relevance. Since their discovery more than 2 decades ago in C. elegans,
1 microRNAs (miRNAs) have emerged as an important class of nonprotein coding RNA …
1 microRNAs (miRNAs) have emerged as an important class of nonprotein coding RNA …
Predicting effective microRNA target sites in mammalian mRNAs
MicroRNA targets are often recognized through pairing between the miRNA seed region
and complementary sites within target mRNAs, but not all of these canonical sites are …
and complementary sites within target mRNAs, but not all of these canonical sites are …
Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development
MicroRNAs (miRNAs) regulate many cellular events during brain development by interacting
with hundreds of mRNA transcripts. However, miRNAs operate nonuniformly upon the …
with hundreds of mRNA transcripts. However, miRNAs operate nonuniformly upon the …
MicroRNA binding sites in the coding region of mRNAs: extending the repertoire of post‐transcriptional gene regulation
It is well established that microRNAs (miRNAs) induce mRNA degradation by binding to 3′
untranslated regions (UTRs). The functionality of sites in the coding domain sequence …
untranslated regions (UTRs). The functionality of sites in the coding domain sequence …
Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA
KM Broadbent, JC Broadbent, U Ribacke, D Wirth… - BMC genomics, 2015 - Springer
Background The human malaria parasite Plasmodium falciparum has a complex and multi-
stage life cycle that requires extensive and precise gene regulation to allow invasion and …
stage life cycle that requires extensive and precise gene regulation to allow invasion and …
MicroRNA detection: current technology and research strategies
EA Hunt, D Broyles, T Head… - Annual review of analytical …, 2015 - annualreviews.org
The relatively new field of microRNA (miR) has experienced rapid growth in methodology
associated with its detection and bioanalysis as well as with its role in-omics research …
associated with its detection and bioanalysis as well as with its role in-omics research …
LncMirNet: predicting LncRNA–miRNA interaction based on deep learning of ribonucleic acid sequences
Long non-coding RNA (LncRNA) and microRNA (miRNA) are both non-coding RNAs that
play significant regulatory roles in many life processes. There is cumulating evidence …
play significant regulatory roles in many life processes. There is cumulating evidence …
In silico methods for predicting functional synonymous variants
Single nucleotide variants (SNVs) contribute to human genomic diversity. Synonymous
SNVs are previously considered to be “silent,” but mounting evidence has revealed that …
SNVs are previously considered to be “silent,” but mounting evidence has revealed that …
Comprehensive overview and assessment of computational prediction of microRNA targets in animals
MicroRNAs (miRNAs) are short endogenous noncoding RNAs that bind to target mRNAs,
usually resulting in degradation and translational repression. Identification of miRNA targets …
usually resulting in degradation and translational repression. Identification of miRNA targets …