High-performance medicine: the convergence of human and artificial intelligence

EJ Topol - Nature medicine, 2019 - nature.com
The use of artificial intelligence, and the deep-learning subtype in particular, has been
enabled by the use of labeled big data, along with markedly enhanced computing power …

The microbiome and innate immunity

CA Thaiss, N Zmora, M Levy, E Elinav - Nature, 2016 - nature.com
The intestinal microbiome is a signalling hub that integrates environmental inputs, such as
diet, with genetic and immune signals to affect the host's metabolism, immunity and …

[HTML][HTML] Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features

N Zmora, G Zilberman-Schapira, J Suez, U Mor… - Cell, 2018 - cell.com
Empiric probiotics are commonly consumed by healthy individuals as means of life quality
improvement and disease prevention. However, evidence of probiotic gut mucosal …

Dysbiosis and the immune system

M Levy, AA Kolodziejczyk, CA Thaiss… - Nature Reviews …, 2017 - nature.com
Throughout the past century, we have seen the emergence of a large number of
multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and …

The human gut microbiome: from association to modulation

TSB Schmidt, J Raes, P Bork - Cell, 2018 - cell.com
Our understanding of the human gut microbiome continues to evolve at a rapid pace, but
practical application of thisknowledge is still in its infancy. This review discusses the type of …

[HTML][HTML] Effects of psychological, environmental and physical stressors on the gut microbiota

JP Karl, AM Hatch, SM Arcidiacono… - Frontiers in …, 2018 - frontiersin.org
Stress, a ubiquitous part of daily human life, has varied biological effects which are
increasingly recognized as including modulation of commensal microorganisms residing in …

Major biological control strategies for plant pathogens

MA Pandit, J Kumar, S Gulati, N Bhandari, P Mehta… - Pathogens, 2022 - mdpi.com
Food security has become a major concern worldwide in recent years due to ever increasing
population. Providing food for the growing billions without disturbing environmental balance …

Plant microbiome engineering: expected benefits for improved crop growth and resilience

I Arif, M Batool, PM Schenk - Trends in Biotechnology, 2020 - cell.com
Plant-associated microbiomes can boost plant growth or control pathogens. Altering the
microbiome by inoculation with a consortium of plant growth-promoting rhizobacteria …

New opportunities in plant microbiome engineering for increasing agricultural sustainability under stressful conditions

MS Afridi, MA Javed, S Ali, FHV De Medeiros… - Frontiers in Plant …, 2022 - frontiersin.org
Plant microbiome (or phytomicrobiome) engineering (PME) is an anticipated untapped
alternative strategy that could be exploited for plant growth, health and productivity under …

Microbiota dysbiosis and barrier dysfunction in inflammatory bowel disease and colorectal cancers: exploring a common ground hypothesis

LCH Yu - Journal of biomedical science, 2018 - Springer
Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the
interaction of genetic, environmental, barrier and microbial factors leading to chronic …