Anti-angiogenic therapy: current challenges and future perspectives
F Lopes-Coelho, F Martins, SA Pereira… - International journal of …, 2021 - mdpi.com
Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …
oxygen supply to the tumor cells through the decrease of the vascular network and the …
[HTML][HTML] Biomarkers in diabetic retinopathy
There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …
An integrative view of serpins in health and disease: the contribution of SerpinA3
A Sánchez-Navarro, I González-Soria… - … of Physiology-Cell …, 2021 - journals.physiology.org
Serpins are a superfamily of proteins characterized by their common function as serine
protease inhibitors. So far, 36 serpins from nine clades have been identified. These proteins …
protease inhibitors. So far, 36 serpins from nine clades have been identified. These proteins …
Human vitreous in proliferative diabetic retinopathy: characterization and translational implications
Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …
age population. DR is a progressive eye disease caused by long-term accumulation of …
Retinal and choroidal angiogenesis: a review of new targets
Retinal and choroidal neovascularization are a major cause of significant visual impairment,
worldwide. Understanding the various factors involved in the accompanying …
worldwide. Understanding the various factors involved in the accompanying …
[HTML][HTML] The cells involved in the pathological process of diabetic retinopathy
S Yang, J Zhang, L Chen - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …
which has not yet been clarified clearly, new insights into retinal physiology indicate that …
Neurovascular cross talk in diabetic retinopathy: Pathophysiological roles and therapeutic implications
Diabetic retinopathy (DR) is the leading cause of blindness in the working-age population in
developed countries, and its prevalence will increase as the global incidence of diabetes …
developed countries, and its prevalence will increase as the global incidence of diabetes …
Ocular therapeutics and molecular delivery strategies for neovascular age-related macular degeneration (Namd)
Age-related macular degeneration (AMD) is the leading cause of vision loss in geriatric
population. Intravitreal (IVT) injections are popular clinical option. Biologics and small …
population. Intravitreal (IVT) injections are popular clinical option. Biologics and small …
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for …
Strong epidemiological and experimental evidence indicate that both age and hypertension
lead to significant functional and structural impairment of the cerebral microcirculation …
lead to significant functional and structural impairment of the cerebral microcirculation …
Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased …
R Fan, L Su, H Zhang, Y Jiang, Z Yu, X Zhang… - Journal of …, 2023 - Springer
Background Several common retinal diseases that cause blindness are characterised by
pathological neovascularisation accompanied by inflammation and neurodegeneration …
pathological neovascularisation accompanied by inflammation and neurodegeneration …