Normal circulatory function is a key determinant of disease-free life expectancy (healthspan).
Indeed, pathologies affecting the cardiovascular system, which are growing in prevalence …

Cardiovascular diseases (CVD) are complex entities with heterogenous pathophysiologic
mechanisms and increased oxidative stress has been viewed as one of the potential …

Vitamin D is known to elicit a vasoprotective effect, while vitamin D deficiency is a risk factor
for endothelial dysfunction (ED). ED is characterized by reduced bioavailability of a potent …

Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the
United States and many developed nations. Two major age-related arterial phenotypes …

Age-related vascular endothelial dysfunction is a major antecedent to cardiovascular
diseases. We investigated whether increased circulating levels of the gut microbiome …

Plasma free fatty acids levels are increased in subjects with obesity and type 2 diabetes,
playing detrimental roles in the pathogenesis of atherosclerosis and cardiovascular …

Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …

Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in both
men and women in developed societies. Age is the greatest risk factor for CVD due largely …

Vascular diseases of the elderly are a topic of enormous interest in clinical practice, as they
have great epidemiological significance and lead to ever-increasing healthcare …

Sarcopenia, the age-related loss of muscle mass and function, imposes a dramatic burden
on individuals and society. The development of preventive and therapeutic strategies …