Studies on the DNA-binding properties of transcription factors are important in searching for
the downstream genes regulated by these factors. In the present study, we report on the …

Bacterial pathogens have developed complex strategies to successfully survive and
proliferate within their hosts. Throughout the infection cycle, direct interaction with host cells …

Talin and vinculin are mechanosensitive proteins that are recruited early to integrin-based
nascent adhesions (NAs). In two epithelial cell systems with well-delineated NA formation …

Chlamydia trachomatis is the leading cause of infectious blindness and a sexually
transmitted infection. All chlamydiae are obligate intracellular bacteria that replicate within a …

Talin (TLN1) is a mechanosensitive component of adhesion complexes that directly couples
integrins to the actin cytoskeleton. In response to force, talin undergoes switch-like behavior …

Focal adhesions (FAs) serve as dynamic signaling hubs within the cell. They connect
intracellular actin to the extracellular matrix (ECM) and respond to environmental cues. In …

Chlamydia pneumoniae is one of the two major species of the Chlamydiaceae family that
have a profound effect on human health. C. pneumoniae is linked to a number of severe …

Talin and vinculin, both actin-cytoskeleton-related proteins, have been documented to
participate in establishing bacterial infections, respectively, as the adapter protein to mediate …

Chlamydiae are obligate intracellular pathogens that require a specialized intracellular
niche for their survival and replication. Hence, they possess an efficient means of gaining …

Vinculin is a protein associated to reinforce integrin adhesion structures. The protein's D1
and D5 subdomains have been extensively studied for its binding capacity to VBSs and F …