Philipp Blanke, MD, a Jonathan R. Weir-McCall, MBCHB, PHD, b Stephan Achenbach, MD,
c Victoria Delgado, MD, PHD, d Jörg Hausleiter, MD, e Hasan Jilaihawi, MD, f Mohamed …

In the vast majority of cardiovascular diseases (CVDs), there are well-described differences
between women and men in epidemiology, pathophysiology, clinical manifestations, effects …

Abstract Aims The Valve Academic Research Consortium (VARC), founded in 2010, was
intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these …

Background Bicuspid aortic stenosis accounts for almost 50% of patients undergoing
surgical aortic valve replacement in the younger patients. Expanding the indication of …

Aims There are limited data on coronary obstruction following transcatheter valve-in-valve
(ViV) implantation inside failed aortic bioprostheses. The objectives of this study were to …

Abstract Objectives: The BASILICA (Bioprosthetic or native Aortic Scallop Intentional
Laceration to prevent Iatrogenic Coronary Artery obstruction during TAVR) investigational …

Transcatheter aortic valve replacement (TAVR) has revolutionized the management of
patients with symptomatic severe aortic stenosis, and indications are expanding towards …

Transcatheter aortic valve implantation (TAVI) has matured into a standard treatment option
for patients with severe symptomatic aortic valve stenosis (AS) across the whole spectrum of …

Abstract Background The Evolut Low Risk Trial (Medtronic Evolut Transcatheter Aortic Valve
Replacement in Low Risk Patients) showed that transcatheter aortic valve replacement …

Objectives: This study sought to develop a novel technique called bioprosthetic or native
aortic scallop intentional laceration to prevent coronary artery obstruction (BASILICA) …