Persistent SARS-CoV-2 infection: significance and implications

HM Machkovech, AM Hahn, JG Wang… - The Lancet infectious …, 2024 - thelancet.com
SARS-CoV-2 causes persistent infections in a subset of individuals, which is a major clinical
and public health problem that should be prioritised for further investigation for several …

Persistent COVID-19 in Immunocompromised Patients–Israeli Society of Infectious Diseases Consensus Statement on Diagnosis and Management

SE Meijer, Y Paran, A Belkin, R Ben-Ami, Y Maor… - Clinical Microbiology …, 2024 - Elsevier
Background Immunocompromised patients with impaired humoral immunity are at risk for
persistent COVID-19 (pCOVID), a protracted symptomatic disease with active viral …

COVID-19 convalescent plasma for the treatment of immunocompromised patients: a systematic review and meta-analysis

JW Senefeld, M Franchini, C Mengoli… - JAMA Network …, 2023 - jamanetwork.com
Importance Patients who are immunocompromised have increased risk for morbidity and
mortality associated with coronavirus disease 2019 (COVID-19) because they less …

Triple combination therapy with 2 antivirals and monoclonal antibodies for persistent or relapsed severe acute respiratory syndrome coronavirus 2 infection in …

M Mikulska, C Sepulcri, C Dentone… - Clinical Infectious …, 2023 - academic.oup.com
Background Severely immunocompromised patients are at risk for prolonged or relapsed
Coronavirus Disease 2019 (COVID-19), leading to increased morbidity and mortality. We …

Case report: Sotrovimab, remdesivir and nirmatrelvir/ritonavir combination as salvage treatment option in two immunocompromised patients hospitalized for COVID-19

F Baldi, C Dentone, M Mikulska, D Fenoglio… - Frontiers in …, 2023 - frontiersin.org
COVID-19 in immunocompromised patients is difficult to treat. SARS-CoV-2 interaction with
the host immune system and the role of therapy still remains only partly understood. There …

[HTML][HTML] Antiviral combination therapies for persistent COVID-19 in immunocompromised patients

D Focosi, F Maggi, A D'Abramo, E Nicastri… - International Journal of …, 2023 - Elsevier
Objectives After the third year of the COVID-19 pandemic, most of the severe COVID-19
burden falls upon immunocompromised patients who cannot mount an endogenous …

Omicron related COVID-19 prevention and treatment measures for patients with hematological malignancy and strategies for modifying hematologic treatment regimes

W Guo, Y Zheng, S Feng - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The Omicron variant of SARS-CoV-2 has rapidly become the dominant strain worldwide due
to its high transmissibility, although it appears to be less pathogenic than previous strains …

[HTML][HTML] Combination treatment of persistent COVID-19 in immunocompromised patients with remdesivir, nirmaltrevir/ritonavir and tixegavimab/cilgavimab

T Brosh-Nissimov, N Ma'aravi, D Leshin-Carmel… - Journal of Microbiology …, 2024 - Elsevier
We present a retrospective study on the treatment outcomes of severely
immunocompromised patients with persistent COVID-19. The study analyzed data from 14 …

Clinical manifestations and risk factors for COVID-19 and its severity in patients with hematological malignancies

TY Wu, WT Tsai, KH Chen, ST Huang… - Journal of Microbiology …, 2024 - Elsevier
Background Patients with hematological malignancies (HM) were at a high risk of
develo** severe disease from coronavirus disease 2019 (COVID-19). We aimed to assess …